1.       2018.01-2021.12    国家自然科学基金面上基金  负责人

2.       2015.01-2016.12    天然产物活性物质与功能国家重点实验室优秀青年基金  负责人

3.       2015.01-2017.12    国家自然科学基金青年基金  负责人

4.       2015.01-2016.12    中国医学科学院“协和新星”基金  负责人

5.       2014.01-2016.12    中国医学科学院药物所创新人才基金  负责人

6.       2013.12-2014.11    中国医学科学院协和青年骨干基金  负责人

7.       2011.07-2013.06    美国心脏学会（AHA）博士后基金  负责人

1. Zhang XW, Zhou JC, Peng D, HuaF, Li K, Yu JJ, Lv XX, Cui B, Liu SS, Yu JM, Wang F, Jin CC, Yang ZN, Zhao CX,Hou XY, Huang B, Hu ZW*. Disrupting the TRIB3-SQSTM1 interaction reduces liverfibrosis by restoring autophagy and suppressing exosome-mediated HSCactivation. Autophagy, 16(5):782-796,2020 (IF: 16.016)

2. Wang XH†, ZhangXW†, Ren XP, Chen J, Liu HZ, Yang JQ, Medvedovic M, Hu ZW, Fan GC*.MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protectsagainst ischemia/ reperfusion-induced cardiac injury. Circulation, 122(13):1308-18, 2010 († co-first author, IF:14.432)

3. Liu P, Bao HY, Jin CC, Zhou JC,Hua F, Li K, Lv XX, Cui B, Hu ZW, ZhangXW*. Targeting Extracellular Heat Shock Protein 70 AmelioratesDoxorubicin-Induced Heart Failure Through Resolution of Toll-Like Receptor2-Mediated Myocardial Inflammation. J Am Heart Assoc, 8(20):e012338, 2019

4. Zhang XW, Sun L, Chen W, Wu SN,Li YM, Li XJ, Zhang B, Yao JY, Wang H, Xu AJ*. ARHGEF4-mediates the actincytoskeleton reorganization of hepatic stellate cells in 3-dimensional collagenmatrices. Cell Adh Migr,13(1):169-181, 2019

5. Jin W, Cui B, Li PP, Hua F, Lv XX,Zhou JC, Hu ZW, Zhang XW*. 1,25-Dihydroxyvitamin D3 protects obese rats from metabolic syndrome via promotingregulatory T cell-mediated resolution of inflammation. Acta Pharm Sin B, 8(2):178-187, 2018

6. Wu RN,Yu TY, Zhou JC, Li M, Gao HK, Zhao C, Dong RQ, Peng D, Hu ZW, Zhang XW*, Wu YQ*. Targeting HMGB1ameliorates cardiac fibrosis through restoring TLR2-mediated autophagysuppression in myocardial fibroblasts. IntJ Cardiol, 267:156-162, 2018 (* co-corresponding author)

7. Zhang XW, Mi S, Li Z, Zhou JC, Xie J, Hua F, Li K, Cui B, Lv XX, Yu JJ, Hu ZW*.Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis byrestoring the IL-10/STAT3-suppressed autophagy in hepatocytes. Oncotarget, 8(6):9922-9934, 2017

8. Zhang XW, Zhou JC, Hu ZW*. Autophagy as a target for development ofanti-diabetes drugs derived from natural compounds. J Asian Nat Prod Res, 19(4):314-319, 2017

9. Zhang XW, Wang XH, Zhu HY, Kranias EG, Tang YL, Peng TQ, Chang J, Fan GC*. Hsp20functions as a novel cardiokine in promoting angiogenesis via activation ofVEGFR2. PLoS One,7(3):e32765, 2012

10. Ma YG†, Zhang XW†, Bao HY, Mi S, Cai WF, Yan HM, Wang QQ, Wang ZY, Yan J, FanGC, Lindsey ML, Hu ZW*. Toll-like receptor (TLR) 2 and TLR4 differentiallyregulate doxorubicin induced cardiomyopathy in mice. PLoS One, 7(7):e40763, 2012 († co-first author)

11. Zhang XW, Wang XH, Zhu HY, Zhu C, Wang YG, Pu WT, Jegga AG, Fan GC*. Synergisticeffects of the GATA4- mediated miR-144/451 cluster in protection againstsimulated ischemia/reperfusion-induced cardiomyocyte death. J Mol Cell Cardiol, 49(5):841-50, 2010

12. Cai WF†, Zhang XW†, Yan HM, MaYG, Wang XX, Yan J, Xin BM, Lv XX, Wang QQ, Wang ZY, Yang HZ, Hu ZW*.Intracellular or extracellular heat shock protein 70 differentially regulatescardiac remodelling in pressure overload mice. Cardiovasc Res, 88(1):140-9, 2010 († co-first author)

13. Jin CC, ZhangXW*. Research progress of natural medicines and bioactive compounds againstheart failure. Acta Pharm Sin, 55(6):1147-1156, 2020

14. Peng D, Hu ZW, Zhang XW*. Therapeutic perspectives of intestinal probiotics A. muciniphila in metabolic disorders. Acta Pharm Sin, 54(5): 768-777, 2019

15. Zhang XW, Cai WF, HuZW*. Advances in the study of immunopathological mechanism of dilatedcardiomyopathy. Advancesin Cardiovascular Diseases,30(5):814-817, 2009

16. Yu JJ, Zhou DD, Cui B, Zhang C, Tan FW, ChangS, Li K, Lv XX, Zhang XW, Shang S,Xiang YJ, Chen F, Yu JM, Liu SS, Wang F, Hu ZW*, Hua F*. Disruption of theEGFR-SQSTM1 interaction by a stapled peptide suppresses lung cancer viaactivating autophagy and inhibiting EGFR signaling. Cancer Lett. 474:23-35, 2019

17. Yu JM, Sun W, Wang ZH, Liang X, Hua F, Li K, LvXX, Zhang XW, Liu YY, Yu JJ, Liu SS,Shang S, Wang F, Yang ZN, Zhao CX, Hou XY, Li PP, Huang B, Cui B*, Hu ZW*.TRIB3 Supports Breast Cancer Stemness by Suppressing FOXO1 Degradation andEnhancing SOX2 Transcription. Nat Commun.10(1):5720, 2019

18. Liu SS, Lv XX, Liu C, Qi J, Li YX, Wei XP, LiK, Hua F, Cui B, Zhang XW, Yu JJ, YuJM, Wang F, Shang S, Zhao CX, Hou XY, Yao ZG, Li PP, Li X, Huang B, Hu ZW*.Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosisby Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages. Immunity, 51(3):522-534.e7, 2019

19. Hua F, Shang S, Yang YW, Zhang HZ, Xu TL, YuJJ, Zhou DD, Cui B, Li K, Lv XX, ZhangXW, Liu SS, Yu JM, Wang F, Zhang C, Huang B, Hu ZW*. TRIB3 Interacts Withβ-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer StemCells and Tumorigenesis. Gastroenterology,156(3):708-721, 2019

20. Cui B, Eyers PA, Dobens LL, Tan NS, Mace PD,Link WA, Kiss-Toth E, Keeshan K, Nakamura T, Pear WS, Feseha Y, Johnston J,Carracedo A, Scheideler M, llyas Z, Bauer RC, Erusalimsky JD, Grzesik D,Salamanca-Viloria J , Lv XX, Jin YS, Li K, Velasco G, Shang S, Lizcano JM, Zhang XW, Zhou JC, Yu JJ, Hua F, WangF, Liu SS, Yu JM, Hu ZW*. Highlights of the 2nd International Symposium onTribbles and Diseases: Tribbles tremble in therapeutics for immunity,metabolism, fundamental cell biology and cancer. Acta Pharm Sin B. 9(2):443-454, 2019

21. Li K, Zhang TT, Wang F, Cui B, Zhao CX, Yu JJ,Lv XX, Zhang XW, Yang ZN, Huang B,Li X, Hua F, Hu ZW. Metformin suppresses melanoma progression by inhibitingKAT5-mediated SMAD3 acetylation, transcriptional activity and TRIB3 expression.Oncogene, 37(22):2967-2981, 2018

22. Li K, Wang F, CaoWB, Lv XX, Hua F, Cui B, Yu JJ, Zhang XW,Shang S, Liu SS, Yu JM, Han MZ, Huang B, Zhang TT, Li X, Jiang JD, Hu ZW*.TRIB3 Promotes APL Progression through Stabilization of the OncoproteinPML-RARα and Inhibition of p53-Mediated Senescence. Cancer Cell, 31(5):697-710, 2017

23. Xie J, Yun JP, Yang YN, Hua F, ZhangXW, Lin H, Lv XX, Li K, Zhang PC, Hu ZW*. A novel ECG analog4-(S)-(2,4,6-trimethylthiobenzyl)-epigallocatechin gallate selectively inducesapoptosis of B16-F10 melanoma via activation of autophagy and ROS. Sci Rep, 7:42194, 2017

24. Cui B, Cao XT, Zou WP, Wan YH, Wang N, Wang YH,Li PP, Hua F, Liu YY, Zhang XW, LiK, Lv XX, Huang B*, Hu ZW*. Regulation of immune-related diseases by multiplefactors: a meeting report of 2017 International Workshop of the Chinese Academyof Medical Sciences Initiative for Innovative Medicine on Tumor Immunology. Acta Pharm Sin B. 7(4):532-540, 2017

25. Qi MY, Zhou JC, Zhang XW,Zhong XG, Zhang YP, Zhang XJ, Deng XL, Li HY, Wang QQ*. Effect of Xiaoqinglongdecoction on mucus hypersecretion in the airways and cilia function in a murinemodel of asthma. J Tradit Chin Med Sci,4:290-296, 2017

26. Hua F, Li K, Yu JJ, Lv XX, Yan J, ZhangXW, Sun W, Lin H, Shang S, Wang F, Cui B, Mu R, Huang B, Jiang JD, Hu ZW*.TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impedingautophagic/proteasomal degradations. NatCommun, 6:7951, 2015

27. Yan HM, Cui Bing, Zhang XW, FuXM, Yan J, Wang XX, Lv XX, Chen Z, Hu ZW*. Antagonism of toll-like receptor 2attenuates the formation and progression of abdominal aortic aneurysm. Acta Pharm Sin B, 45(3):176-187, 2015

28. Wang XH, Zhu HY, Zhang XW, LiuY, Chen J, Medvedovic M, Li HL, Weiss MJ, Ren XP, Fan GC*. Loss of themiR-144/451 cluster impairs ischaemic preconditioning- mediatedcardioprotection by targeting Rac-1. Cardiovasc Res, 94(2):379-90, 2012

29. Yan J, Wang ZY, Yang HZ, Liu HZ, Mi S, Lv XX, Fu XM, Yan HM, Zhang XW, Zhan QM, Hu ZW*. Timing iscritical for an effective anti-metastatic immunotherapy: the decisive role ofIFNγ/STAT1-mediated activation of autophagy. PLoS One, 6(9):e24705, 2011

30. Wang QQ, Yang HZ, Liu HZ, Mi S, ZhangXW, Yan HM, Ma YG, Wang XX, Hu ZW*. Interleukin-17A is involved indevelopment of spontaneous pulmonary emphysema caused by Toll-like receptor 4mutation. Acta Pharmacol Sin, 32(8):1045-54,2011

31. Xin BM, Wang XX, Jin W, Yan HM, Cui B, Zhang XW, Hua F, Yang HZ, Hu ZW*. Activation of Toll-like receptor9 attenuates unilateral ureteral obstruction-induced renal fibrosis. Acta Pharmacol Sin, 31(12):1583-92,2010

1. 吕晓希，张晓伟，胡卓伟. 自噬流检测的意义和方法. 谢志平等编著：自噬-生物学与疾病·技术卷（第三版）. 科学出版社, 2021

2. 张晓伟，胡卓伟.  血管及血压调节的分子机制及药物应用. 王晓良等编著：应用分子药理学（第二版）. 中国协和医科大学出版社, 2015

3. 胡卓伟，张晓伟. 调节心脏组织重构和心肌再生治疗慢性心血管疾病. 王晓良等编著：应用分子药理学（第二版）. 中国协和医科大学出版社，2015

4. 吕晓希，张晓伟，胡卓伟. 自噬流检测的意义和方法. 秦正红等编著：自噬-生物学与疾病（第二版）. 科学出版社, 2015

5. 张晓伟，严君，胡卓伟.  皮肤纤维化实验方法和技术.  张均田等编著：现代药理实验方法（第二版）. 中国协和医科大学出版社，2012

6. 张晓伟，杨红振，贲长恩.  重要的促纤维化因子和抑纤维化因子. 牛建昭等编著：器官纤维化基础及中医药防治. 人民卫生出版社，2008

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