承担项目

主持国家自然科学基金面上基金项目1项（红花中羟基红花黄色素A生物合成相关单加氧酶及其生物合成应用的研究，81773427，2020.01-2023.12），主持国家自然科学基金青年基金项目1项（库拉索芦荟中芦荟苷生物合成关键酶C-糖基转移酶的功能鉴定及其C-糖基化应用，81602999，2017.01-2019.12）；作为子课题负责人或骨干人员参与了中国医学科学院医学与健康科技创新工程、国家“十三五”重大新药创制专项等多项课题。

发表论文

1.     Kebo Xie, Ridao Chen, Jianhua Li, Ruishan Wang, Dawei Chen, Xiaoxiang Dou, and Jungui Dai*, Exploring the Catalytic Promiscuity of a New Glycosyltransferase from Carthamustinctorius, Organic Letters, 2014, 16, 4874-4877. (IF 6.56)

2.     Kebo Xie, Ridao Chen, Dawei Chen, Jianhua Li, Ruishang Wang, Lin Yang and Jungui Dai*, Enzymatic N-Glycosylation of Diverse Arylamine Aglycones by a Promiscuous Glycosyltransferase from Carthamus tinctorius. Advanced Synthesis & Catalysis, 2017, 359, 603‒608. (IF 5.45)

3.      Kebo Xie#, Xiaoxiang Dou#, Ridao Chen, Dawei Chen, Cheng Fang, Zhiyan Xiao and Jungui Dai*, Molecular Characterization and Phylogenetic Analysis of Two Novel Fungal Phenolic UDP-Glycosyltransferases from Absidia coerulea and Rhizopus japonicus. Applied and Environmental Microbiology, 2017, AEM-03103. (IF 3.63)

4.     Huili Li#, Kebo Xie#, Wenjun Yu, Liejie Hu, Haiyan Huang, Huijun Xie and Shuning Wang*, Nicotine dehydrogenase complexed with 6-hydroxypseudooxynicotine oxidase involved in the hybrid nicotine-degrading pathway in Agrobacterium tumefaciens S33. Applied and Environmental Microbiology, 2016, 82, 1745‒1755. (IF 3.63，共同一作)

5.     Tian Yue, Ridao Chen, Dawei Chen, Jimei Liu, Kebo Xie* and Jungui Dai*, Enzymatic Synthesis of Bioactive O-Glucuronides Using Plant Glucuronosyltransferases, Journal of Agricultural and Food Chemistry, 2019, 67, 6275-6284. (IF 3.41, 共同通讯作者)

6.     Kebo Xie, Yujiao Zhang, Ridao Chen, Dawei Chen, Lin Yang, Xia Liu and Jungui Dai*, Enzymatic glucosylation of unnatural naphthols by a promiscuous glycosyltransferase fromAloe arborescens. Tetrahedron Letters, 2017, 58, 2118‒2121. (IF 2.13)

7.     Dawei Chen, Ridao Chen, Ruishan Wang, Jianhua Li, Kebo Xie, et al. Probing the catalytic promiscuity of a regio- and stereospecific C-glycosyltransferase from Mangifera indica. Angewandte Chemie International Edition, 2015, 54, 12678‒12682. (IF 12.26)

专利

1.     一种芦荟C-糖基转移酶序列及其在催化C-糖基化中的应用，申请号：201811485713.6

2.     一类碳糖苷类化合物及其制备和用途，申请号：201910521052.6

3.     一种香豆素衍生物代谢产物的制备及其在防治脑缺血和阿尔茨海默病中的应用.申请号：201710261815.9

4.     光学活性双环醇葡萄糖苷及其制备方法和防治肝病的应用.申请号：201811483811.6

5.     一种C-糖基转移酶、其核酸序列及其在催化C-糖基化中的应用.申请号：201510679254.5