1)  十四五国家重点研发计划重点专项，2022YFC2504003，基于肠道菌群、脑-肠轴及肠道微环境的IBS潜在药物靶点研究，2023/01-2027/12，参与

2）国家自然科学基金面上基金，81470540，T淋巴细胞在α1肾上腺素受体自身抗体诱导的高血压血管损伤中的作用研究，主持

3）国家自然科学基金青年科学基金，81000107，高血压大鼠对α1肾上腺素受体自身抗体缩血管效应敏感性改变及其机制探讨，主持

4） 医学电生理四川省重点实验室开放基金，2011-01，α1肾上腺素受体自身抗体对高血压大鼠血管活动和平滑肌细胞钙离子通道的作用研究，主持

5）中国博士后科学基金面上项目，20100470246，α1肾上腺素受体自身抗体在高血压发生发展中的作用研究，主持

6） 中国医学科学院医学与科技创新工程项目，2017-I2M-1-008，代谢与能量失衡在重大疾病发生发展中的研究：代谢与能量失衡在心血管疾病中的作用及机制，参与

7） 国家重点研发计划重点专项，2017YFA0205504，铁基纳米材料类酶效应与急性髓系白血病诊疗技术，参与

8） 973课题，2011CB933504，纳米材料对血液免疫功能细胞的作用及其在白血病免疫治疗中的新方法研究，参与

9）国家自然基金青年基金，81300139，急性心肌梗死时心脏交感神经活性变化的动力学研究，参与

1. Qin Xiaohan#, Lei Chuxiang#, Yan Li#, et al. Proteomic and Metabolomic Analyses of Right Ventricular Failure due toPulmonary Arterial Hypertension, Front Mol Biosci, 2022, 9: 834179.

2. Huang Yongfa#, Lei Chuxiang#, Xie Wenjun#,Yan Li#, et al. Oxidation of Ryanodine ReceptorsPromotes Ca2+ Leakage and Contributes to Right VentricularDysfunction in Pulmonary Hypertension, 2021, 77(1):59-71.

3. Zhao HM#, Song XM#, Yan L#, et al. IgEinduces hypotension in asthma mice by down-regulating vascular NCX1 expressionthrough activating MiR-212-5p. BBA -Molecular Basis of Disease. 2018; 1864(1): 189-196.

4. Li H#,Tan XQ#, Yan L# , et al. Multi-walledcarbon nanotubes act as a chemokine and recruit macrophages by activatingthe  PLC/IP3/CRAC channel signalingpathway. Sci Rep. 2017;7: 226.

5. Yan L#,Liu X, Liu WX, et al. Fe2O3 nanoparticles suppress Kv1.3channels via affecting the redox activity of Kvβ2 subunit in Jurkat T cells. Nanotechnology. 2015; 26(50):505103.

6. Yan L#,Tan XQ#, Chen WX，Zhu H, Cao JM. Enhancedvasoconstriction to α1 adrenoceptor autoantibody in spontaneouslyhypertensive rats. Sci China Life Sci. 2014;57(7):681-689.

7. Yan L, XuYW, Yao H, Xue WX, Tian J, Ren HQ, Wu Y, Yang GZ, Ma XL, Liu HR. The effects ofautoantibodies against the second extracellular loop of α1-adrenoceptor onvasoconstriction. Basic Res Cardiol.2009; 104(5):581-589.

8. Zhu H, Yan L,Gu JL, et al. Kv1.3 channel blockade enhances the phagocytic function ofRAW264.7 macrophages. Sci China LifeSci. 2015; 58(9):867-75.

9. Du YH, Yan L,Wang J, et al. b1-adrenergic receptor autoantibodiesfrom heart failure patients enhance the proliferation and secretion of Tlymphocytes through the b1-AR/cAMP/PKA and p38 MAPKpathways. PLoS One. 2012;7(12):e52911.

10. Du YH, Yan L,Quan L, et al. b1-adrenergic receptor autoantibodiesfrom heart failure patients enhanced TNF-a secretion in RAW264.7macrophages in a largely PKA-dependent fashion. J Cell Biochem. 2012; 113(10):3218-28.

11. Liu Y, Zhou L,Xu HF, Yan L, et al. A preliminary experimental study on thecardiac  toxicity of glutamate and therole of α-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid receptor in rats.Chin Med J (Engl). 2013; 126(7):1323-32.

12. Wang C,Qiu WY, Zheng YQ, Li H, Li YJ, Feng B, Guo S, Yan L, et al. Extraneuronal monoamine transporter mediates the permissive action of cortisol in the guinea pig trachea: possible involvement of tracheal chondrocytes. PLoSOne. 2013;8(10):e76193.