教育背景

2005.9-2008.7   中国医学科学院药物研究所   药物化学  博士

2001.9-2004.7   山东省医学科学院药物研究所  天然药物化学  硕士

1997.9-2001.7   山东大学药学院  药学   学士 

工作经历

2017.10-至今     中国医学科学院药物研究所  副研究员

2008.9-2017.9   中国医学科学院药物研究所  助理研究员

2004.9-2005.7   山东省医学科学院药物研究所  实习研究员

代表性论文

1.   Rao Wei#, Leilei Zhang#, Shengnan Xu, Qingyang Zhang, Yongxiu Qi, Hai-yu Hu*. A single component self-assembled thermally activated delayed fluorescence nanoprobe. Chem Commun (Camb). 2020, 56(17), 2550-2553.

2.   Leilei Zhang#, Yun Liu#, QingyangZhang, Tiegang Li, Min Yang, Qingqiang Yao, Xilei Xie, Hai-Yu Hu*. Gadolinium-Labeled Aminoglycoside and Its Potential Application as a Bacteria-Targeting Magnetic Resonance Imaging Contrast Agent. Anal Chem. 2018, 90(3), 1934-1940.

3.   Leilei Zhang, Yan Yu, Zijie Liu, Zeper Abliz, Gang Liu*. Identification of peptide substrateand small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays. Journal of Medicinal Chemistry, 2009, 52, 4419-4428. 

4.   Yun Liu#, Leilei Zhang*#, Marc Nazare, Qingqiang Yao, Hai-Yu Hu*. A Novel Nitroreductase-enhanced MRI Contrast Agentand its Potential Application in Bacterial Imaging. Acta Pharmaceutica Sinica B, 2018, 8(3), 401-408.

5.   Leilei Zhang, Tianming Yang, Xilei Xie, Gang Liu*. Identification of 3, 5, 6-substituted indolin-2-one’s inhibitors of aurora B bydevelopment of a luminescent kinase assay. Bioorganic ＆Medicinal Chemistry Letters, 2015, 25, 2937-2942.

6.   Leilei Zhang*#, Yan Wang#,Dequan Yu*. Simultaneous quantification of six major triterpenoid saponins in Schefflera kwangsiensis using high-performance liquid chromatography coupled to orbitrap mass spectrometry. Natural product research, 2015, 29,1350-1357.

7.   Leilei Zhang, Shengquan Hu, Lei Lei, Yuliang Zhang, LijingZhang, Hongrui Song, Zhufang Shen, Zhiqiang Feng*. Design, Synthesis and Evaluation of Novel Derivatives of Orotic Acid Amide as Potent Glucokinase Activators. Letters in Drug Design & Discovery, 2017, 14, 252- 261.

8.   Leilei Zhang, Zhiqiang Feng*. The stereoselective C-alkylation of chiral nitronic acid (4S﹡, 5R)-(+)-4-(6-nitro-6-carbethoxymethyl)-5-[(1R)-menthyloxy]-3,4-dihydro-2(5H)-furanone. J. Indian Chem. Soc., 2014, 91, 1335-1339.

9.   张蕾磊，薛海，李莉，陆小凡，陈志伟，刘刚*. (±)-F18对映异构体的HPLC手性分离、绝对构型确定以及抗HIV-1活性研究。药学学报，2015，50， 733-737.

 专利

1. 胡海宇, 张青扬, 王庆华, 张蕾磊, 许胜男。一种孔雀石绿类荧光探针分子、其制备及其在细菌，细胞成像中的应用，申请号: 201710463705.0.