近五年承担项目：

代表性论著：

1.  Xinhua Xiao, et al. Evidence of a relationship between infant birth weight and later d iabetes and impaired glucose regulation in a Chinese population. Diabetes Care. 2008; 31(3): 483–487.

2.  Min Jiang, Xinhua Xiao*, et al. Lack of testicular seipin causes teratozoospermia syndrome in men. Proc Natl Acad Sci U S A. 2014; 111(19): 7054-9.

3. Xiaojing Wang,  Xinhua Xiao*, et al. Localized increases in CEPT1 and ATGL elevate plasmalogen phosphatidylcholines in HDLs contributing to atheroprotective lipid profiles in hyperglycemic GCK-MODY. Redox Biol. 2021 Apr;40:101855.

4.  Xinhua Xiao, et al. Low Birth Weight is Associated With Components of the Metabolic Syndrome. Metabolism. 2010; 59 (9): 1272-1276.

5. Qian Zhang, Xinhua Xiao*, et al. Maternal Inulin Supplementation Alters Hepatic DNA Methylation Profile and Improves Glucose Metabolism in Offspring Mice. Frontiers in physiology. 2020; 11:70. 

6. Junling Fu, Xinhua Xiao*, et al. Primary hepatocellular adenoma due to biallelic HNF1A mutations and its co-occurrence with MODY 3: case-report and review of the literature. Endocrine. 2020; 67 (3): 544-551. 

7. Liyuan Zhou, Xinhua Xiao*, et al. Gut microbiota might be a crucial factor in deciphering the metabolic benefits of perinatal genistein consumption in dams and adult female offspring. Food & function. 2019; 10 (8): 4505-4521. 

8. Liyuan Zhou, Xinhua Xiao*, et al. A Possible Mechanism: Genistein Improves Metabolism and Induces White Fat Browning Through Modulating Hypothalamic Expression of Ucn3, Depp, and Stc1. Front Endocrinol (Lausanne). 2019; 10 478. 

9. Liyuan Zhou, Xinhua Xiao*, et al. Deciphering the Anti-obesity Benefits of Resveratrol: The "Gut Microbiota-Adipose Tissue" Axis. Front Endocrinol (Lausanne). 2019; 10 413.

10. Liyuan Zhou, Xinhua Xiao*, et al. Maternal Genistein Intake Mitigates the Deleterious Effects of High-Fat Diet on Glucose and Lipid Metabolism and Modulates Gut Microbiota in Adult Life of Male Mice. Frontiers in physiology. 2019; 10 985. 

11. Qian Zhang, Xinhua Xiao*, et al. Influence of Maternal Inulin-Type Prebiotic Intervention on Glucose Metabolism and Gut Microbiota in the Offspring of C57BL Mice. Front Endocrinol (Lausanne). 2019; 10 675.

12. Qian Zhang, Xinhua Xiao*, et al. A Maternal High-Fat Diet Induces DNA Methylation Changes That Contribute to Glucose Intolerance in Offspring. Front Endocrinol (Lausanne). 2019; 10 871. 

13. Xinhua Xiao, et al. Achieving the composite end-point of glycated hemoglobin <7.0% without weight gain or hypoglycemia with once-weekly dulaglutide in Chinese patients with type 2 diabetes: A post-hoc analysis. Journal of diabetes investigation. 2019.

14. Zhixin Wang, Xinhua Xiao*, et al. Identification and functional analysis of GCK gene mutations in 12 Chinese families with hyperglycemia. Journal of diabetes investigation. 2019; 10 (4): 963-971. 

15. Xiaojing Wang, Xinhua Xiao*, et al. Screening of HNF1A and HNF4A mutation and clinical phenotype analysis in a large cohort of Chinese patients with maturity-onset diabetes of the young. Acta diabetologica. 2019; 56 (3): 281-288. 

16. Fan Ping, Xinhua Xiao*, et al. Clinical and enzymatic phenotypes in congenital hyperinsulinemic hypoglycemia due to glucokinase-activating mutations: A report of two cases and a brief overview of the literature. Journal of diabetes investigation. 2019; 10 (6): 1454-1462. 

17. Junling Fu, Xinhua Xiao*, et al. Birthweight correlates with later metabolic abnormalities in Chinese patients with maturity-onset diabetes of the young type 2. Endocrine. 2019; 65 (1): 53-60. 

18. Junling Fu, Xinhua Xiao*, et al. Identification of insulin gene variants in patients with neonatal diabetes in the Chinese population. Journal of diabetes investigation. 2019.

19. Mingqun Deng, Xinhua Xiao*, et al. First Case Report of Maturity-Onset Diabetes of the Young Type 4 Pedigree in a Chinese Family. Front Endocrinol (Lausanne). 2019; 10 406. 

20. Liyuan Zhou, Xinhua Xiao*, Qian Zhang, Jia Zheng, Li M, Yu M, Xiaojin Wang, Mingqun Deng, Zhai X, Li R, et al. Improved Glucose and Lipid Metabolism in the Early Life of Female Offspring by Maternal Dietary Genistein Is Associated With Alterations in the Gut Microbiota. Front Endocrinol (Lausanne). 2018; 9 516. 

21. Jia Zheng, Xinhua Xiao*, et al. Maternal nutrition and the developmental origins of osteoporosis in offspring: Potential mechanisms and clinical implications. Experimental biology and medicine. 2018; 243 (10): 836-842. 

22. Jia Zheng, Xinhua Xiao*, et al. Physical Exercise and Its Protective Effects on Diabetic Cardiomyopathy: What Is the Evidence? Front Endocrinol (Lausanne). 2018; 9 729. 

23. Jia Zheng, Xinhua Xiao*, et al. Curcumin, A Polyphenolic Curcuminoid With Its Protective Effects and Molecular Mechanisms in Diabetes and Diabetic Cardiomyopathy. Frontiers in pharmacology. 2018; 9 472.

24. Qian Zhang, Xinhua Xiao*, et al. Featured article: Structure moderation of gut microbiota in liraglutide-treated diabetic male rats. Experimental biology and medicine. 2018; 243 (1): 34-44. 

25. Qian Zhang, Xinhua Xiao*, et al. Compound Danshen Dripping Pill Inhibits Retina Cell Apoptosis in Diabetic Rats. Frontiers in physiology. 2018; 9 1501. 

26. Qian Zhang, Sun X, Xinhua Xiao*, et al. Maternal chromium restriction induces insulin resistance in adult mice offspring through miRNA. International journal of molecular medicine. 2018; 41 (3): 1547-1559. 

27. Zhixin Wang, Xinhua Xiao*, et al. Preliminary screening of mutations in the glucokinase gene of Chinese patients with gestational diabetes. Journal of diabetes investigation. 2018; 9 (1): 199-203.

28. Jia Zheng, Xinhua Xiao*, et al. Maternal Low-Protein Diet Modulates Glucose Metabolism and Hepatic MicroRNAs Expression in the Early Life of Offspring dagger. Nutrients. 2017; 9 (3).

29. Jia Zheng, Xinhua Xiao*, Qian Zhang, Mao L, Yu M, Xu J, Tong Wang, et al. The Placental Microbiota Is Altered among Subjects with Gestational Diabetes Mellitus: A Pilot Study. Frontiers in physiology. 2017; 8 675. 

30. Qian Zhang, Xinhua Xiao*, et al. Maternal chromium restriction modulates miRNA profiles related to lipid metabolism disorder in mice offspring. Experimental biology and medicine. 2017; 242 (14): 1444-1452.

31. Jia Zheng, Xinhua Xiao*, et al. Maternal high-calorie diet is associated with altered hepatic microRNA expression and impaired metabolic health in offspring at weaning age. Endocrine. 2016; 54 (1): 70-80. 

32. Jia Zheng, Xinhua Xiao*, et al. Early Life Fructose Exposure and Its Implications for Long-Term Cardiometabolic Health in Offspring. Nutrients. 2016; 8 (11).

33. Qian Zhang, Xinhua Xiao*, et al. Effects of Maternal Chromium Restriction on the Long-Term Programming in MAPK Signaling Pathway of Lipid Metabolism in Mice. Nutrients. 2016; 8 (8).

34. Qian Zhang, Xinhua Xiao*, et al. Maternal Chromium Restriction Leads to Glucose Metabolism Imbalance in Mice Offspring through Insulin Signaling and Wnt Signaling Pathways. International journal of molecular sciences. 2016; 17 (10).

35. Jia Zheng, Xinhua Xiao*, et al. Maternal protein restriction induces early-onset glucose intolerance and alters hepatic genes expression in the peroxisome proliferator-activated receptor pathway in offspring. Journal of diabetes investigation. 2015; 6 (3): 269-279. 

36. Jia Zheng, Xinhua Xiao*, et al. The Placental Microbiome Varies in Association with Low Birth Weight in Full-Term Neonates. Nutrients. 2015; 7 (8): 6924-6937. 

37. Yun Zhang, Xinhua Xiao*, et al. Role of high-risk variants in the development of impaired glucose metabolism was modified by birth weight in Han Chinese. Diabetes metabolism research and reviewers. 2015; 31 (8): 790-795.

38. Jianping Xu, Xinhua Xiao*, et al. The effect of gum chewing on blood GLP-1 concentration in fasted, healthy, non-obese men. Endocrine. 2015; 50 (1): 93-98. 

39. Jia Zheng, Xinhua Xiao*, et al. Maternal high-fat diet modulates hepatic glucose, lipid homeostasis and gene expression in the PPAR pathway in the early life of offspring. International journal of molecular sciences. 2014; 15 (9): 14967-14983. 

40. Jia Zheng, Xinhua Xiao*, et al. DNA methylation: the pivotal interaction between early-life nutrition and glucose metabolism in later life. British Journal of nutrition. 2014; 112 (11): 1850-1857. 

41. Qian Zhang, Xinhua Xiao*, et al. miR-375 and miR-30d in the effect of chromium-containing Chinese medicine moderating glucose metabolism. Journal of diabetes research. 2014; 2014 862473.

42. Qian Zhang, Xinhua Xiao*, et al. Telmisartan improves kidney function through inhibition of the oxidative phosphorylation pathway in diabetic rats. Journal of molecular endocrinology. 2012; 49 (1): 35-46. 

43. Qian Zhang, Xinhua Xiao*, et al. Gene expression profiling in glomeruli of diabetic nephropathy rat. Experimental biology and medicine. 2012; 237 (8): 903-911. 

44. Yun Zhang, Xinhua Xiao*, et al. The association of the PAX4 gene with type 1 diabetes in Han Chinese. Diabetes Research and clinical practice. 2008; 81 (3): 365-369.

45. 虞睿琪,付俊玲,肖新华*.特殊类型糖尿病的临床识别[J].中国实用内科杂志,2020,40(01):19-24.

46. 翟笑,刘洁颖,李融融,刘俊涛,宋英娜,马良坤,乔宗旭,赵贵芬,王瑞平,张茜,邓明群,付俊玲,周丽媛,赵楠,宋玮,肖新华*.小于胎龄儿母婴血浆中甜菜碱的水平及其与孕妇糖代谢的关系[J].医学研究杂志,2019,48(12):36-40.

47. 李融融,肖新华*.盘点2017年糖尿病治疗的临床营养实践及研究进展[J].医学研究杂志,2018,47(03):168-171.

48. 周丽媛,肖新华*.肠道菌群与糖尿病的免疫发病机制:表观遗传调控[J].医学研究杂志,2018,47(02):9-12.

49. 王晓晶,王彤,于淼,张化冰,平凡,张茜,许建萍,冯凯,李文慧,郑佳,肖新华*.12例暴发性1型糖尿病临床特征分析[J].中国糖尿病杂志,2018,26(01):69-73.

50. 肖新华*.糖尿病前期的药物干预[J].医学研究杂志,2017,46(12):1-2.

51. 赵谧,肖新华*.糖尿病前期人群早期干预治疗进展[J].医学研究杂志,2017,46(11):186-189.

52. 陈美婷,肖新华*.间充质干细胞改善糖尿病相关机制的研究进展[J].医学研究杂志,2017,46(09):17-20.

53. 林新杰,肖新华*.胆固醇、他汀类药物与帕金森病关系的研究进展[J].中华老年多器官疾病杂志,2017,16(06):464-467.

54. 王中华,陈艳华,徐婧,陈蕙莉,周霞,肖新华*,平凡,贺玖明,再帕尔·阿不力孜,张瑞萍.血清脂质组学研究中多重离子化液相色谱-质谱方法的比较[J].分析化学,2017,45(05):674-680.

55. 林泽明,肖新华*.胰岛细胞转分化及相关转录因子的研究进展[J].医学研究杂志,2017,46(03):182-185.

56. 王晓晶,肖新华*.2型糖尿病口服降糖药治疗[J].临床荟萃,2016,31(09):939-943.

57. 黎婧怡,许莉军,姜艳,邱正庆,姚凤霞,李文慧,肖新华*,邢小平.一例含葡萄糖-6-磷酸酶新突变的复合杂合突变致华人糖原累积症Ia型的遗传特点[J].协和医学杂志,2016,7(04):264-268.

58. 王晓晶,肖新华*.DPP-4抑制剂与二甲双胍固定剂量复合剂的疗效综合评价[J].药品评价,2016,13(07):18-23.

59. 李伟,肖新华*.先天性高胰岛素血症[J].医学研究杂志,2016,45(01):12-16.

60. 郑佳,肖新华*,张茜,于淼,许建萍,王志新,齐翠娟,王彤.母鼠和断乳后高脂饮食诱导子代雄鼠出现糖脂代谢异常及肠道菌群失调的实验观察[J].中国糖尿病杂志,2015,23(11):1018-1022.

61. 张茜,肖新华*,黎明,李文慧,于淼,张化冰,平凡,杨国华.糖尿病肾病大鼠肾脏差异表达基因研究[J].医学研究杂志,2015,44(06):16-19.

62. 张茜,肖新华*,黎明,李文慧,于淼,张化冰,平凡,杨国华.复方血栓通胶囊改善肾功能机制研究[J].天津中医药,2015,32(06):359-363.

63. 张茜,肖新华*,黎明,李文慧,于淼,张化冰,平凡,王志新,郑佳.天麦消渴片通过miRNA改善糖尿病大鼠血糖的机制[J].中国实验动物学报,2015,23(01):1-6.

64. 肖新华.以始为终:预混胰岛素治疗1-2-3[J].药品评价,2015,12(03):39-42+45.

65. 王彤,肖新华*.心力衰竭是二甲双胍的绝对禁忌证吗[J].药品评价,2015,12(01):30-35.

66. 郑佳,肖新华*,张茜,于淼,许建萍,王志新,刘一静,李明敏.母鼠营养不良导致子代在生命早期出现糖脂代谢紊乱及其机制探讨[J].遗传,2015,37(01):70-76.

67. 郑佳,肖新华*,张茜,于淼,许建萍,王志新.母代高脂饮食诱导子代在小鼠生命早期出现糖脂代谢紊乱且具有雄性易感性[J].中国实验动物学报,2014,22(04):6-11+99.

68. 郑佳,肖新华*.宫内和出生后早期发育环境对成年期糖代谢影响的中枢调控作用机制[J].中国实验动物学报,2014,22(04):77-80.

69. 张茜,肖新华*.microRNA与糖尿病发生发展机制的关系[J].中国糖尿病杂志,2014,22(06):574-576.

70. 陈适,肖新华*,童安莉,王鸥,于康,邱正庆.1例高胰岛素高血氨综合征诊断与治疗随访[J].基础医学与临床,2014,34(01):36-40.

71. 许建萍,肖新华*.胰高血糖素样肽-1的生理作用及分泌调节因素[J].中华临床医师杂志(电子版),2013,7(24):11632-11634.

72. 郑佳,肖新华*.表观遗传修饰在糖尿病慢性并发症中的研究进展[J].中国糖尿病杂志,2013,21(10):952-954.

73. 习聪,陈艳华,杨维,张瑞萍,贺玖明,张化冰,肖新华*,再帕尔·阿不力孜.脂质组学血清样品处理方法及其快速高分辨液相色谱-质谱分析[J].分析化学,2013,41(09):1308-1314.

74. 刘巍,陈适,肖新华*,王莹.西格列汀治疗脆性糖尿病一例并文献复习[J].中华临床医师杂志(电子版),2013,7(16):7436-7439.

75. 许建萍,肖新华*,陈适,连小兰,袁涛,段炼,顾锋,李玉秀,邢小平,向红丁.垂体脓肿合并垂体瘤一例[J].中华临床医师杂志(电子版),2013,7(16):7664-7665.

76. 许建萍,李玉秀,伍学焱,邢小平,肖新华*.高渗性非酮症糖尿病昏迷合并横纹肌溶解一例[J].中华临床医师杂志(电子版),2013,7(01):447-449.

77. 张茜,肖新华*,黎明,李文慧,李伟,于淼,张化冰,平凡,孙晓方,茅李莉,杨国华.替米沙坦改善糖尿病大鼠肾脏功能机制研究[J].中国实验动物学报,2012,20(06):10-14.

78. 许建萍,平凡,李梅,余卫,夏维波,肖新华*,邢小平.罕见的Proteus综合征一例报道并文献复习[J].中华临床医师杂志(电子版),2012,6(13):3636-3640.

79. 孙晓方,屈克义,黄汉涛,张茜,石贵昌,茅李莉,仝小林,向红丁,肖新华*.天芪降糖胶囊预防2型糖尿病:一项在中国糖耐量减低患者中进行的随机、双盲、安慰剂对照研究[J].中国糖尿病杂志,2011,19(06):433-436.

80. 孙晓方,陈适,卢琳,邱正庆,肖新华*.糖原累积病Ⅰ b型1例的临床和分子遗传分析[J].基础医学与临床,2011,31(05):529-533.

81. 茅李莉,肖新华*,刘英,朱席琳,孙晓方,张茜,李文慧,于淼,张化冰.胰岛素—胰岛素样生长因子代谢轴在胎儿生长发育中的作用[J].中国糖尿病杂志,2011,19(03):204-206.

82. 陈思,肖新华*.新生儿糖尿病的分子诊断[J].中国新生儿科杂志,2011,26(02):143-144.

83. 张茜,肖新华*,王彤,朱席琳,李文慧,刘英,袁涛,孙晓方,孙琦,向红丁,王姮.黄连素降糖调脂机制的研究[J].中国实验动物学报,2011,19(01):29-33+93.

84. 茅李莉,肖新华*.多囊卵巢综合征的临床处理[J].实用糖尿病杂志,2010,6(03):3-4.

85. 刁呈明,萨仁图雅,肖新华*,孙晓方,茅李莉,张茜,李文慧,于淼,袁涛,黎明,向红丁,王姮.两个MODY2中国家系葡萄糖激酶基因杂合突变的研究[J].中国糖尿病杂志,2010,18(06):405-408.

86. 付勇,李玉秀,肖新华*,王姮.青少年1型和2型糖尿病患者临床特点和鉴别诊断分析[J].中国糖尿病杂志,2010,18(06):416-418.

87. 孙晓方,肖新华*.院内高血糖控制及管理[J].内科急危重症杂志,2010,16(01):4-7+16.

88. 徐燕,朱燕,李乃适,卢琳,庄俊玲,葛昌文,周佳鑫,陈适,朱铁楠,王书杰,肖新华*,夏维波,邢小平.以骨量低下、多发骨破坏为首发临床表现的急性淋巴细胞白血病[J].中华骨质疏松和骨矿盐疾病杂志,2009,2(04):272-276.

89. 孙晓方,肖新华*.暴发性1型糖尿病的研究进展[J].中国全科医学,2009,12(16):1544-1546.

90. 刁呈明,肖新华*.单基因突变导致的糖代谢异常的遗传学分类及临床提示[J].医学研究杂志,2009,38(08):7-9.

91. 张茜,肖新华*,王彤,李文慧,袁涛,孙晓方,孙琦,向红丁,王姮.应用基因芯片探讨天芪降糖胶囊降糖调脂的机制[J].中国糖尿病杂志,2009,17(03):174-177.

92. 李文慧,肖新华*,于康,孙琦,杨国华,王姮,Ole Schmitz.短期高脂饮食对中国汉族男性2型糖尿病患者糖脂代谢的影响[J].中国医学科学院学报,2008(04):509-515.

93. 张云,肖新华*,王姮,王彤,孙琦,杨国华,付勇,袁涛,张茜,刘秋英.PAX4基因A1168C多态性与中国汉族人1型糖尿病的相关性[J].中国医学科学院学报,2007(03):370-373.