王淼教授于2013年回国，组建科研团队。现有成员~20人，包括研究助理2名、技术员2名、博士后2名、博士生6名、硕士生3名、联合培养硕士研究生3名。课题组各项工作顺利进行，并取得重要进展。培养的博士后获得了美国心脏学会（AHA）ATVB大会论坛青年研究者奖、协和青年学者、国家自然基金委青年基金、国家博士后基金、北自然青年科学基金，有1人已评上副高职称；培养的研究生获得了ATVB大会论坛青年研究者奖、Paul Dudley White国际学者奖、ATVB旅行奖，协和医学院校长奖、优秀毕业生、世界微循环大会"青年学者”奖、美国心脏协会科学年会“旅行奖”等荣誉。

冠心病的炎症调控机制、基于机制的药物发现。

炎症、血栓疾病的调控机制与创新治疗。

1)     A biomarker framework for cardiac aging: the Aging Biomarker Consortiumconsensus statement. Life Medicine,  Published: 2023

2)      A framework of biomarkers for vascular aging: A consensus statementby the Aging Biomarker Consortium（血管衰老生物标志物框架：中国衰老标志物研究联合体共识）. Aging Biomarker Consortium (中国衰老标志物研究联合体), Le Zhang, Jun Guo, Yuehong Liu,Shimin Sun, Baohua Liu, Qi Yang, Jun Tao, Xiao-Li Tian, Jun Pu, Huashan Hong,Miao Wang (共同通讯), Hou-Zao Chen, Jie Ren, Xiaoming Wang, Zhen Liang, Yuan Wang, KaiHuang, Weiqi Zhang, Jing Qu, Zhenyu Ju, Guang-Hui Liu, Gang Pei, Jian Li,Cuntai Zhang. Life Medicine. 2023; https://doi.org/10.1093/lifemedi/lnad033   Life Medicine,   Published: 30 August 2023

3)     Peng Z, Chen H, Wang M*(*通讯作者). Identificationof the biological processes, immune cell landscape, and hub genes shared byacute anaphylaxis and ST-segment elevation myocardial infarction. FrontPharmacol. 2023;14:1211332. doi: 10.3389/fphar.2023.1211332.

4)     Zhang Y, Steinmetz-Späh J,Idborg H, Zhu L, Li H, Rao H, Chen Z, Guo Z, Hu L, Xu C, Chen H, Korotkova M,Jakobsson PJ*, Wang M* (*通讯作者). Microsomal prostaglandin E synthase-1 inhibition prevents adversecardiac remodeling after myocardial infarction in mice. Br J Pharmacol. 2023;180(15):1981-1998.

5)     Wan Q, Xu C, Zhu L, Zhang Y,Peng Z, Chen H, Rao H, Zhang E, Wang H, Chu F, Ning X, Yang X, Yuan J, Wu Y,Huang Y, Hu S, Liu DP, Wang M* (*通讯作者). Targeting PDE4B (Phosphodiesterase-4 Subtype B) for Cardioprotectionin Acute Myocardial Infarction via Neutrophils and Microcirculation. CircRes. 2022;131(5):442-55.

6)     Tang Y, Jia Y, Fan L, Liu H, ZhouY, Wang M, Liu Y, Zhu J, Pang W, Zhou J. MFN2 Prevents Neointimal Hyperplasiain Vein Grafts via Destabilizing PFK1. Circ Res. 2022;130(11):e26-e43.

7)     Zhang Y, Li H, Huang Y, Chen H,Rao H, Yang G, Wan Q, Peng Z, Bertin J, Geddes B, Reilly M, Tran JL, Wang M* (*通讯作者). Stage-Dependent Impact of RIPK1 Inhibition on Atherogenesis: Dual Effectson Inflammation and Foam Cell Dynamics. Front CardiovascMed. 2021;8:715337

8)     Wang Y, Wang M, SamuelCS, Widdop RE. Preclinical rodent models of cardiac fibrosis. Br JPharmacol. 2022 Mar;179(5):882-899.

9)     Hao H, Ma X, Chen H, Zhu L, XuZ, Li Q, Xu C, Zhang Y, Peng Z, Wang M*(*通讯作者). Thecyclic adenosine monophosphate elevating medicine, forskolin, reducesneointimal formation and atherogenesis in mice. J Cell Mol Med. 2020;24(17):9638-9645

10)  Zhu L, Zhang Y, Guo Z, Wang M * (*通讯作者). Cardiovascular Biology of Prostanoidsand Drug Discovery. Arterioscler Thromb Vasc Biol. 2020;40(6):1454-1463. (特邀综述)

11)  Platelet factor 4 enhances CD4+ T effector memory cell responses viaAkt-PGC1α-TFAM signaling-mediated mitochondrial biogenesis. Tan S, Li S, Min Y,Gisterå A, Moruzzi N, Zhang J, Sun Y, Andersson J, Malmström RE, Wang M,Berggren PO, Schlisio S, Liao W, Ketelhuth DFJ, Ma C, Li N. JThromb Haemost. 2020;18(10):2685-2700.

12)  Qing Wan, Siyuan Qian, Yonghu Huang, Yuze Zhang, Zekun Peng,Qiaoling Li, Bingyan Shu, Liyuan Zhu, Miao Wang* (*通讯作者). DrugDiscovery for Coronary Artery Disease. AdvExp Med Biol. 2020;1177:297-339.

13)  Peng Z, Shu B, Zhang Y, Wang M * (*通讯作者). EndothelialResponse to Pathophysiological Stress. Arterioscler ThrombVasc Biol. 2019;39(11):e233-e243. (特邀综述)

14)  Zhu L, Xu C, Huo X, Hao H, Wan Q, Chen H, Zhang X, Breyer RM, HuangY, Cao X, Liu DP, FitzGerald GA, Wang M* (*通讯作者). The cyclooxygenase-1/mPGES-1/endothelialprostaglandin EP4 receptor pathway constrains myocardial ischemia-reperfusion injury.NatCommun. 2019;10(1):1888.

15)  Chen L, Yang G, Jiang T, Tang SY, Wang T, Wan Q, Wang M,FitzGerald GA. Myeloid Cell mPges-1 Deletion Attenuates Mortality Without AffectingRemodeling After Acute Myocardial Infarction in Mice. J Pharmacol Exp Ther. 2019;370(1):18-24.

16)  Hao H#, Tian W#, Pan C, Jiao Y, Deng X, Fan J, Han J, Han S*, WangM*(*通讯作者), Li P*. Marsdenia tenacissimaextract dilated small mesenteric arteries via stimulating endothelial nitricoxide synthase and inhibiting calcium influx. J Ethnopharmacol. 2019;238:111847.

17)  Wang M* (*通讯作者), Hao H,Leeper NJ, Zhu L. Thrombotic regulation from the endothelial cell perspectives.ArteriosclerThromb Vasc Biol. 2018;38(6):e90-e95. (特邀综述)

18)  Hao H, Hu S, Wan Q, Xu C, Chen H, Zhu L, Xu Z, Meng J, Breyer RM, LiN, Liu DP, FitzGerald GA, Wang M* (*通讯作者).Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE2(Prostaglandin E2) and the Endothelial EP4 (Prostaglandin E Receptor) in VascularResponses to Injury. Arterioscler Thromb Vasc Biol.2018;38(5):1115-1124.

19)  Miao X, Rahman MF, Jiang L, Min Y, Tan S, Xie H, Lee L, Wang M,Malmström RE, Lui WO, Li N. Thrombin-reduced miR-27b attenuates plateletangiogenic activities in vitro via enhancing platelet synthesis ofanti-angiogenic thrombospondin-1. J Thromb Haemost. 2018;16(4):791-801.

20)  Hao H, Hu S, Chen H, Bu D, Zhu L, Xu C, Chu F, Huo X, Tang Y, Sun X,Ding B, Liu D, Hu S, Wang M* (*通讯作者). Loss ofEndothelial CXCR7 Impairs Vascular Homeostasis, and Cardiac Remodeling AfterMyocardial Infarction: Implications for Cardiovascular Drug Discovery. Circulation.2017; 135(13):1253-1264.

21)  Guo X, Fan C*, Wang Y, Wang M*(*通讯作者), Cai C,Yang Y, Zhao S, Duan F, Li Y. Genetic anticipation in a special form ofhypertrophic cardiomyopathy with sudden cardiac death in a family with 74 membersacross 5 generations. Medicine. 2017 Mar;96(11):e6249.

22)  Yao Y, Tang XF, Zhang JH, He C, Ma YL, Xu JJ, Song Y, Liu R, MengXM, Song L, Chen J, Wang M, Xu B, Gao RL, Yuan JQ Association of PEAR1genetic variants with platelet reactivity in response to dual antiplatelettherapy with aspirin and clopidogrel in the Chinese patient population after percutaneouscoronary intervention. Thromb Res. 2016 May;141:28-34

23)  Yao Y, Zhang JH, Tang XF, He C, Ma YL, Xu JJ, Song Y, Liu R, MengXM, Song L, Wang M, Gao RL, Yuan JQ. Head to Head Comparison of Two Point-of-carePlatelet Function Tests Used for Assessment of On-clopidogrel PlateletReactivity in Chinese Acute Myocardial Infarction Patients UndergoingPercutaneous Coronary Intervention. Chin Med J. 2016;129(19):2269-74.

24)  Wang M* (*通讯作者), Jin W, Guo AM, StubbeJ. Cardiovascular Inflammation. Mediators of Inflammation. 2013,2013:123513.

25)  Knight DR, Smith AH, Schroeder RL, Huang C, Beebe DA,Sokolowski SA, Wang M* (*通讯作者). Effects of age onnoninvasive assessments of vascular function in nonhuman primates: implicationsfor translational drug discovery. J Transl Med.2013:11:101. doi: 10.1186/1479-5876-11-101

26) Lowell AN, Qiao H, Liu T, IshikawaT, Zhang H, Oriana S, Wang M, Ricciotti E, FitzGerald GA, Zhou R, andYamakoshi Y. Functionalized Low-Density Lipoprotein Nanoparticles for in Vivo Enhancementof Atherosclerosis on Magnetic Resonance Images. BioconjugateChem. 2012; 23(11):2313-9.

27)  Wang M, Fitzgerald GA.The cardiovascular biology of microsomal prostaglandin E synthase-1. Trends Cardiovasc Med. 2011; 20(6): 189–195.

28)  Wang M* (*通讯作者), Ihida-Stansbury K,Kothapalli D, Tamby MC, Yu Z, Chen L, Grant G, Cheng Y, Lawson JA, Assoian RK,Jones PL, Fitzgerald GA*. MicrosomalProstaglandin E2 Synthase-1 Modulates the Response to VascularInjury. Circulation. 2011;123(6):631-9.

29)  Hui Y, Crichton I, Ricciotti E, Yu Z, Wang D,Stubbe J, Wang M, Puré E, FitzGerald GA. Targeted Deletions of COX-2 andAtherogenesis in Mice. Circulation. 2010;121(24):2654-60.

30)  Wang M* (*通讯作者), Jiang M, Cooper PR, Zhao H, Hui Y, Yao Y, Tate JC, DameraG, Lawson JA., Jester WF, Panettieri RA and FitzGerald GA. Deletion ofmicrosomal Prostaglandin E Synthase does not alter ozone-induced airwayhyper-responsiveness. J Pharmacol Exp Ther. 2010;334(1):63-8.

31)  Damera G, Zhao H, Wang M, Smith M, KirbyC, Jester WF, Lawson JA, Panettieri RA Jr. Ozone modulates IL-6 secretion inhuman airway epithelial and smooth muscle cells. Am J Physiol Lung Cell MolPhysiol. 2009;296(4):L674-83.

32)  Smyth EM, Grosser T, Wang M,Yu Y, FitzGerald GA. Prostanoids inhealth and disease. J Lipid Res. 2009; 50: S423 - S428.

33)  Wang Y, Barthold J, Figueroa E, González R, NohPH, Wang M, Manson J. Analysis of five single nucleotide polymorphismsin the ESR1 gene in cryptorchidism. Birth Defects Res A ClinMol Teratol. 2008;82(6):482-5.

34)  Wang M, Song W-L and FitzGerald GA. Microsomal prostaglandin Esynthase–1 inhibition in cardiovascular inflammatory disease. JIntern Med. 2008;263(5):500-5.

35)  Wang M, Lee E, Song W-L, Ricciotti E, Rader DJ, Lawson JA, Puré Eand FitzGerald GA.  Microsomal PGESynthase-1 Deletion Suppresses Oxidative Stress and Angiotensin II InducedAbdominal Aortic Aneurysm Formation. Circulation. 2008;117(10):1302-9.

36)  Song WL, Wang M, Ricciotti E, Fries S, YuY, Grosser T, Reilly M, Lawson JA, FitzGerald GA. Tetranor PGDM: An abundanturinary metabolite reflects biosynthesis of PGD2 in mice and humans.JBiol Chem. 2008;283(2):1179-88.

37)  Song WL, Lawson JA, Wang M,Zou H, FitzGerald GA. NoninvasiveAssessment of the Role of Cyclooxygenases in Cardiovascular Health: A DetailedHPLC/MS/MS Method. Methods in Enzymol. 2007;433:51-72.

38)  Wang M, Zukas AM, Hui Y, Ricciotti E, Puré E and FitzGerald GA.Deletion of microsomal PGE synthase -1 augments prostacyclin and retardsatherogenesis. Proc Natl Acad Sci USA. 2006; 103(39):14507-12.

39)  Cheng Y+, Wang M+ (+ co-1st authorship), Yu Y+, Lawson JA, Funk CD and FitzGerald GA.Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascularfunction. J Clin Invest. 2006;116(5):1391-9.[Commentary: Peter Kirkpatrick. New clues in the COX2 mystery. NatureReviews Drug Discovery. 2006, 55: 4571]

40)  Wang D, Wang M, Cheng Y, FitzGerald GA.Cardiovascular hazard and non-steroidal anti-inflammatory drugs. CurrOpin Pharmacol. 2005, 5(2):204-10.

41)  Egan KM, Wang M, Lucitt MB,Zukas AM, Puré E, LawsonJA and FitzGerald GA. Cyclooxygenases,Thromboxane, and Atherosclerosis: Plaque Destabilization by Cyclooxygenase-2Inhibition Combined With Thromboxane Receptor Antagonism. Circulation,2005, 111(3): 334-342. 

42)  Wang M, Chen L, WangL, Han Y, Zou Y, Si J, Song G. Expression of Human Papillomavirus Type 6 L1 andL2 Isolated in Chinaand Self Assembly of Virus-like Particles by the Products. ActaBiochimica et Biophysica Sinica, 2003, 35(1): 27-34.

2010  美国费城科学论坛服务优秀奖

2010  美国动脉粥样硬化、血栓及血管生物学科学委员会青年科学家旅行奖

2012  国家第七批“千人计划（青年项目）”（海外高层次人才支持计划）

2017  入选中国医学科学院“高端科技人才”专项支持计划（优秀青年人才）

2017  中国共产党中国医学科学院阜外医院委员会 阜外医院 先进个人 称号

2018  中国医学科学院北京协和医学院“青年创新奖”

2018  中国医学科学院阜外医院心血管疾病国家重点实验室“优秀科研人员”称号

2019  药明康德生命化学研究奖学者奖（缺血性心脏病炎症调节机制与治疗干预）

2019  中国医学科学院阜外医院先进个人

2021  北京协和医学院研究生课程《冠心病治疗与新药发现》“我最喜爱的阜外授课老师”【北京协和医学院中国医学科学院阜外医院教育处】

2021 科技部“科技创新领军人才”

2022 中组部第六批“万人计划”（国家高层次人才特殊支持计划）

2023 所负责的“冠心病治疗与新药发现”课程入选北京协和医学院研究生精品课程

2023 全国归侨侨眷先进个人

美国心脏协会资深会员（AHA fellow，2021至今）

中国老年学和老年医学学会老年病学分会 常务委员（2021年5月）

Standing member of GerontologyCouncil, China Association of Gerontology and Geriatrics

中国生理学会血栓与止血专业委员会委员（2019年至今）Committee Member of Thrombosis and Hemostasis Council,Chinese Association for Physiological Sciences.

中国病理生理学会受体与信号转导委员会委员（2021年至今）CommitteeMember of Receptors and Signal Transduction Council, Chinese Association for Pathophysiology.

美中医药开发协会（SAPA）终身会员（2005年起、2009-2010年度任大费城分会常务理事）

美国华人抗体协会（CAS）终身会员

美国华人心脏学会(CAAC)终身会员（执行委员会委员2020至今）

美国心脏学会会员(AHA，2005年至现在)

中国病理生理学会-国际心脏研究会中国分会（ISHRC）会员  Member of Chinesebranch of International Heart Research Association

美国心脏协会（AHA）科学年会（Scientific Sessions）组委会委员（Program committee member，全球总共约35人，2022至今）

美国动脉硬化、血栓与血管生物学科学年会（Scientific Sessions）组委会委员（Program committee member，2018至今)

美国心脏学会(AHA) 动脉硬化、血栓与血管生物学（ATVB）青年委员会委员（2016.7–2021.6）

美国心脏学会科学年会(AHA Scientific Sessions) 2016摘要评委，2017、2018 、2019、2020 AHA科学年会青年研究者奖评委

香港研究资助局（Research Grants Council）基金评委（2020至今）

美国华人心脏学会（CAAC）论坛评委（2014年11月）；

美国ATVB-CAAC-MPVB(中国自然基金委重大血管专项计划)/CSVM(中国血管医学学会)联合论坛（2015、2016、2017、2018、2019年）会议组织者

美国心脏学会(AHA)基金评委2009

中国心脏大会（CHC）2013、2015、2016、2017、2018心血管基础论坛组织者和主持人 【心血管基础科学论坛执行委员会委员】

美国第十一届年度冬季廿〔烷〕酸大会墙报评委

Redox Biology期刊（Q1，影响因子: 11.8）编辑委会委员/Editorial BoardMember 2020年4月-

Frontiers in Physiology期刊（影响因子: 4.8）评审编辑/Review Editor 2020年5月-

Biochemical Pharmacology期刊（Q1，影响因子: 5.8）Editorial Advisory Board 2023年9月

期刊Mediators of Inflammation的特约专辑(Cardiovascular inflammation)编委(Invited Lead Guest Editor)

期刊特约审稿人Biochemical Pharmacology; PhysiologicalGenomics; Mediators of Inflammation; Frontiers in Pharmacotherapy ofInflammation； BiotechnologyProgress；中华心血管病杂志；中国循环杂志；生理学进展；中国医学科学院学报；

期刊Mediators of Inflammation的特约专辑(Cardiovascularinflammation)编委(Invited Lead Guest Editor)

期刊特约审稿人Biochemical Pharmacology; Physiological Genomics;Mediators of Inflammation; Frontiers in Pharmacotherapy of Inflammation； BiotechnologyProgress

“冠心病治疗与新药发现” 课程负责人

”药理学疾病模型和药效评价“ 授课

“病原免疫学” 授课

“科研导论” 授课    

”学术能力构建I“ 授课