1、高尔基蛋白73对肝细胞癌的诊断和治疗的价值；

2、建立新的肝癌血清标记物GP73酶联免疫检测方法；

3、新型CTC检测技术对肝癌的早期诊断、疗效评估和复发监测的作用；

4、TCM细胞治疗对胆管细胞癌根治术后预防复发的作用机制研究；

5、肝癌的多学科综合治疗。

1.Yilei Mao, Huayu Yang, Haifeng Xu, Xin Lu, Xinting Sang, Shunda Du, Haitao Zhao, Wang Chen, Yiyao Xu, Tianyi Chi, Zhiying Yang, Jianqiang Cai, Hui Li, Jianguo Chen, Shouxian Zhong, Smruti Mohanti, Reynold Lopez-Soler, J. Michael Millis, Jiefu Huang, Hongbing Zhang. Golgi Protein 73 (GOLPH2) Is a Valuable Serum Marker for Hepatocellular Carcinoma. Gut 2010; 59: 1687-1693（IF13.319）（共同第一作者）

2.Junyu Long , Jianzhen Lin , Anqiang Wang , Liangcai Wu , Yongchang Zheng , Xiaobo Yang , Xueshuai Wan , Haifeng Xu, Shuguang Chen, Haitao Zhao. PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapy. Journal of Hematology & Oncology (2017) 10:146（IF 6.350）（通讯作者）

3.Huayu Yang , Haifeng Xu , Yanan Wang , Jinchun Zhang , Xinting Sang , Yilei Mao. Clinicopathologic correlations of Golgi protein 73 and signal transducer and activator of transcription 3 expression in hepatocellular carcinoma. Transl Cancer Res 2017;6(1):238-246 （IF 1.167）（通讯作者）

4.    Huayu Yang , Ziyi Yang , Xinting Sang, Yilei Mao, Xin Lu, Shouxian Zhong, Haifeng Xu*. Diagnosis and treatment of primary hepatic lymphoma. Transl Cancer Res 2018;7(3):720-728.（IF 1.167）（通讯作者）

5.  Yongchang Zheng, Xin Wang, Feihu Xie, Zhaoqi Gu, Li He, Shunda Du, Haitao Zhao, Yiyao Xu, Xin Lu, Yilei Mao, Xinting Sang, Haifeng Xu*, Tianyi Chi*.  Research progress on DNA methylation in hepatocellular carcinoma. Transl Cancer Res 2017;6(5):981-998. （IF 1.167）（第一通讯作者）

6.  Xu G, Yang HY, Xu HF. Prediction of microvascular invasion in hepatocellular carcinoma with preoperative imaging radiomic analysis: Is it ready for prime time?. Hepatobiliary Pancreat Dis Int. 2019

7.  Xu G, Sun L, Li Y, Xie F, Zhou X,Yang H, Du S, Xu H and Mao Y (2019) The Clinicopathological and Prognostic Value of PD-L1 Expression in Cholangiocarcinoma: A Meta-Analysis. Front. Oncol. 9:897. doi: 10.3389/fonc.2019.00897（IF 4.137）（通讯作者）

8.  Wenfang Dong, Bin Qiu, Haifeng Xu, Le-ren He. Invasive management of symptomatic hepatic hemangioma.  European Journal of Gastroenterology & Hepatology.  2019;31(9): 1079-1084（IF2.198）（通讯作者）

9.XU Hai-feng, MAO Yi-lei, DU Shun-da, CHI Tian-yi, LU Xin, YANG Zhi-ying, SANG Xin-ting, ZHONG Shou-xian, HUANG Jie-fu. Adult primary undifferentiated embryonal sarcoma of the liver: a case report. Chinese Medical Journal. 2010; 123(2): 250-252. （IF1.016）