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2005年毕业于华中科技大学生命学院获学士学位；2008年在华中科技大学同济医学院免疫学系完成硕士阶段学习；2012年在法国南巴黎十一大学免疫学专业获得博士学位。后曾在法国国立健康与卫生研究院（INSERM） U1138 Guido Kroemer 实验室做博士后，主要研究肿瘤细胞有免疫原性的死亡方式。2015年以副研究员身份加入苏州系统医学研究所，主要开展肿瘤免疫原性，肿瘤早期诊断和肿瘤疫苗开发等研究。第一作者或通讯作者发表的文章有Nature Medicine，Cell Research， STTT， Small methods， Cancer Research， Oncoimmunology等； 共作者的文章有Science， Immunity， Nature Communication等。目前主持国家，江苏省和中国医学科学院多项自然科学基金项目，2017年获江苏省双创博士称号，2018年作为核心成员获得江苏省双创团队项目资助，2019年获江苏省研究员职称和协和医学院硕士生导师。
代表作：
1.Tianqi Sui, Xiaoyang Wang, Lili Li, Junxiao Liu, Yu Chen, Jinfeng Wang, Qiuxiang Cheng, Nan Qiao, Wancheng Liu, Lihuan Duan, Minxin Shi, Jianfei Huang, Heng Yang* and Gen-hong Cheng* GOLM1 suppresses autophagy-mediated anti-tumor immunity in hepatocellular carcinoma Signal Transduction and Targeted Therapy 2021， proofreading
2.Lili Li, Meiling Gao, Jie Li, Shulong Zu, Yanan Wang, Chunfeng Chen, Dingyi Wan, Jing Duan, Roghiyh Aliyari, Jingfeng Wang, Jicai Zhang, Yujie Jin, Weijin Huang, Xiaoxia Jin, Minxin Shi, Youchun Wang, Cheng-Feng Qin, Heng Yang*, Genhong Cheng* Methods to Identify Immunogenic Peptides in SARS-CoV-2 Spike and Protective Monoclonal Antibodies in COVID-19 Patients Small methods 2021 Online, doi: 10.1002/smtd.202100058
3. Zu, S.*, Deng, Y. Q., Zhou, C., Li, J., Li, L., Chen, Q., Li, X. F., Zhao, H., Gold, S., He, J., Li, X., Zhang, C., Yang, H.†, Cheng, G.†, & Qin, C. F.† (2020). 25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor. Cell research, 30(11), 1043–1045.
4. Yang, H. (#), Xia, L., Chen, J., Zhang, S., Martin,V., Li, Q., Lin, S., Chen, J., Calmette, J., Lu, M., et al. 2019.Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumorimmunity. Nat Med 25:1428-1441.
5. Yang, Heng(#);Yamazaki, Takahiro; Pietrocola, Federico; Zhou, Heng; Zitvogel, Laurence; Ma,Yuting(*); Kroemer, Guido(*), STAT3 Inhibition Enhances the TherapeuticEfficacy of Immunogenic Chemotherapy by Stimulating Type 1 InterferonProduction by Cancer Cells. , Cancer Res, 2015.9.15, 75(18): 3812~3822
6. Yang, Heng(#);Ma, Yuting; Chen, Guo; Zhou, Heng; Yamazaki, Takahiro; Klein, Christophe;Pietrocola, Federico; Vacchelli, Erika; Souquere, Sylvie; Sauvat, Allan;Zitvogel, Laurence; Kepp, Oliver; Kroemer, Guido, Contribution of RIP3 and MLKLto immunogenic cell death signaling in cancer chemotherapy. , Oncoimmunology,2016.6, 5(6): e1149673~e1149673
7. Yang, Heng(#);Yamazaki, Takahiro; Pietrocola, Federico; Zhou, Heng; Zitvogel, Laurence; Ma,Yuting; Kroemer, Guido,Improvement of immunogenic chemotherapy by STAT3 inhibition.Oncoimmunology, 2016.2, 5(2): e1078061~e1078061
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支持扩展名：.rar .zip .doc .docx .pdf .jpg .png .jpeg本人承担的主要科研项目名称 项目来源 起止时间 本人支配科研经费 本人承担任务
新型冠状病毒特异性抗原肽筛选及诊断治疗技术开发中国医学科学院中央级公益性科研院所基本科研业务费项目2020-11-01-2021-10-31 200万元 负责人
高尔基膜蛋白1（GOLM1）对肝细胞癌肿瘤免疫原性的影响及机制探讨国家自然科学基金（面上项目）2021-01-2024.12 55万元 负责人
I型组蛋白去乙酰化酶家族在肿瘤免疫原性调控中的作用及机制国家自然科学基金（青年项目）2019.01-2021.12 25万元 负责人
表达在调节性T细胞上的离子通道分子Trpm4在抗肿瘤免疫应答中的作用江苏省自然科学基金（青年项目）2017.07-2020.06 25万元 负责人
探讨I型组蛋白去乙酰化酶家族在肿瘤免疫原性调控中的作用及机制北京协和医学院基本业务费（青年教师项目）2018.01-2019.12 15万元负责人
代表作：
1. Tianqi Sui, Xiaoyang Wang, Lili Li, Junxiao Liu, Yu Chen, Jinfeng Wang, Qiuxiang Cheng, Nan Qiao, Wancheng Liu, Lihuan Duan, Minxin Shi, Jianfei Huang, Heng Yang* and Gen-hong Cheng* GOLM1 suppresses autophagy-mediated anti-tumor immunity in hepatocellular carcinoma Signal Transduction and Targeted Therapy 2021， proofreading
2. Lili Li, Meiling Gao, Jie Li, Shulong Zu, Yanan Wang, Chunfeng Chen, Dingyi Wan, Jing Duan, Roghiyh Aliyari, Jingfeng Wang, Jicai Zhang, Yujie Jin, Weijin Huang, Xiaoxia Jin, Minxin Shi, Youchun Wang, Cheng-Feng Qin, Heng Yang*, Genhong Cheng* Methods to Identify Immunogenic Peptides in SARS-CoV-2 Spike and Protective Monoclonal Antibodies in COVID-19 Patients Small methods 2021 Online, doi: 10.1002/smtd.202100058
3. Zu, S.*, Deng, Y. Q., Zhou, C., Li, J., Li, L., Chen, Q., Li, X. F., Zhao, H., Gold, S., He, J., Li, X., Zhang, C., Yang, H.†, Cheng, G.†, & Qin, C. F.† (2020). 25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor. Cell research, 30(11), 1043–1045.
4. Yang, H. (#), Xia, L., Chen, J., Zhang, S., Martin,V., Li, Q., Lin, S., Chen, J., Calmette, J., Lu, M., et al. 2019.Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumorimmunity. Nat Med 25:1428-1441.
5. Yang, Heng(#);Yamazaki, Takahiro; Pietrocola, Federico; Zhou, Heng; Zitvogel, Laurence; Ma,Yuting(*); Kroemer, Guido(*), STAT3 Inhibition Enhances the TherapeuticEfficacy of Immunogenic Chemotherapy by Stimulating Type 1 InterferonProduction by Cancer Cells. , Cancer Res, 2015.9.15, 75(18): 3812~3822
6. Yang, Heng(#);Ma, Yuting; Chen, Guo; Zhou, Heng; Yamazaki, Takahiro; Klein, Christophe;Pietrocola, Federico; Vacchelli, Erika; Souquere, Sylvie; Sauvat, Allan;Zitvogel, Laurence; Kepp, Oliver; Kroemer, Guido, Contribution of RIP3 and MLKLto immunogenic cell death signaling in cancer chemotherapy. , Oncoimmunology,2016.6, 5(6): e1149673~e1149673
7. Yang, Heng(#);Yamazaki, Takahiro; Pietrocola, Federico; Zhou, Heng; Zitvogel, Laurence; Ma,Yuting; Kroemer, Guido,Improvement of immunogenic chemotherapy by STAT3 inhibition.Oncoimmunology, 2016.2, 5(2): e1078061~e1078061
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