1. 科技部国家重点研发计划，2020-2024、环境应激和营养失衡所致获得性形状及其代际传递机制、科研骨干。
2. 科技部国家重点研发计划，2016-2020、建立并验证调控ESC自我更新和发育多能性网络调控模型、科研骨干。
3. 国家自然基金委员会优秀青年基金，2022-2025、RNA与造血调控、主持。
4. 国家自然基金委员会面上项目，2020-2024、hnRNPLL调控造血干细胞发育及多能行维持的功能和机制研究、主持。
5. 国家自然基金委员会面上项目，2018-2022、长非编码RNA BGLT3激活胎儿期血红蛋白的功能及机制研究、主持。
6. 国家自然基金委员会面上项目，2016-2020、RNA结合蛋白RBM10调控胚胎干细胞多能性的功能和机制研究、主持。
7. 国家自然基金委员会青年基金，2016-2020、miR-221～222簇在小鼠胚胎干细胞及诱导性多能干细胞中的功能机制研究、主持。
8. 北京市科技新星，2017-2020、RNA结合蛋白参与调控胚胎干细胞多能性的功能机制研究、主持。
9. 中国医学科学院“医学青年人才奖励项目”，2018-2019、长非编码RNA Lnc-Ery-A激活胎儿期血红蛋白的功能及机制研究、主持。

中国医学科学院“医学与健康科技创新工程”创新团队项目，2016-2020、染色质互作分子在细胞命运决定中的功能及作用机制研究、科研骨干。

      造血谱系发育及稳态维持受到精密而复杂的内在程序调控，解码该过程背后的控制程序是指导体外血细胞再生、治疗血液系统疾病的基础。人类基因组80%非编码区域可转录产生RNA是ENCODE计划最为重要的发现之一，而大量非编码RNA的发现为我们解码造血调控程序打开了新的窗口。多年来，马艳妮博士围绕造血谱系分化，聚焦非编码RNA及其协作蛋白，揭示了多种类型非编码RNA参与造血调控的新机制，发现多个RNA结合蛋白调控干细胞命运及造血谱系分化，并建立了RNA研究的新技术与方法。

代表性论著 († first author; * corresponding author):

1.Yanni Ma*, Zhongyang Chen, Jia Yu*. Pseudogenes and their potential functions in hematopoiesis. Experimental Hematology. 2021 Sep 10:S0301-472X(21)00292-7. 

2.Fengjiao Wang†, Jiahuan He†, Siqi Liu†, Ai Gao, Liu Yang, Guohuan Sun, Wanqiu Ding, Chuanyun Li, Fanglin Gou, Manman He, Fang Wang, Xiaoshuang Wang, Xiangnan Zhao, Ping Zhu, Shao Hao, Yanni Ma*, Hui Cheng*, Jia Yu*, Tao Cheng*. Comprehensive RNA editome reveals edited Azin1 as a novel DDX1 partner to facilitate hematopoietic stem cell differentiation. Blood. 2021 Nov 18;138(20):1939-1952.

3.Yanni Ma†*, Siqi Liu†, Jie Gao†, Chunyan Chen†, Xin Zhang†,Hao Yuan, Zhongyang Chen, Xiaolin Yin, Chenguang Sun, Yanan Mao, Fanqi Zhou, YiShao, Qian Liu, Jiayue Xu, Li Cheng, Daqi Yu, Pingping Li, Ping Yi, Jiahuan He,Guangfeng Geng, Qing Guo, Yanmin Si, Hualu Zhao, Haipeng Li, Graham L Banes, HeLiu, Yukio Nakamura, Ryo Kurita, Yue Huang, Xiaoshuang Wang, Fang Wang, GangFang, James Douglas Engel, Lihong Shi*,Yong E Zhang*, Jia Yu*. Genome-wideanalysis of pseudogenes reveals HBBP1's human-specific essentiality inerythropoiesis and implication in β-thalassemia. Developmental Cell. 2021Jan 12:S1534-5807(20)31025-X. 

4.Xue Wang†, Changyun Ping†, Puwen Tan†,Chenguang Sun, Guang Liu, Tao Liu, Shuchun Yang, Yanmin Si, Lijun Zhao, YongfeiHu, Yuyan Jia, Xiaoshuang Wang, Meili Zhang, Fang Wang, Dong Wang*, Jia Yu*, Yanni Ma*,Yue Huang*. hnRNPLL controls pluripotency exit ofembryonic stem cells by modulating alternative splicing of Tbx3 and Bptf. EMBO J. 2020 Dec 422:e104729.

5.Kai Li†, Jiayue Xu†, Yanyun Luo†,Dingfeng Zou, Ruiqin Han, Shunshun Zhong, Qing Zhao, Xinyu Mang , Mengzhen Li,Yanmin Si , Yan Lu, Pengyu Li, Cheng Jin, Zhipeng Wang, Fang Wang, ShiyingMiao, Bo Wen, Linfang Wang, Yanni Ma*, Jia Yu*,Wei Song*. Panoramic transcriptome analysis and functionalscreening of long noncoding RNAs in mouse spermatogenesis. Genome Res. 2021Jan;31(1):13-26.

 6.Zhengyi Zhang†,Jingnan Pi†, Dongling Zou†, Xiaoshuang Wang†, Jiayue Xu†, Shan Yu, Ting Zhang, Feng Li, Hualu Zhao, FangWang, Dong Wang*, Yanni Ma*, Jia Yu*. microRNA arm-imbalance partiallyfrom targets-mediated decay promotes gastric cancer progression. Nature Communications. 2019 Sep. 10 (1):4397.

7.Jie Zhou†, Jiayue Xu†, LinglingZhang†, Siqi Liu†, Yanni Ma†, Xin Wen, Junkai Hao, Zongcheng Li, Yanli Ni, XianlongLi, Fan Zhou, Qingqing Li, Fang Wang, Xiaoshuang Wang, Yanmin Si, PengchengZhang, Chen Liu, Marisa Bartolomei, Fuchou Tang, Bing Liu*, Jia Yu*, and YuLan*. Combined Single-Cell Profiling of lncRNAs and Functional ScreeningReveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development. Cell Stem Cell. 2019 Feb 7. 24; 285-298

8.Ma Y†, Yao N†, Liu G†, Dong L, Liu Y, Zhang M, Wang F, Wang B, Wei X,Dong H, Wang L, Ji S, Zhang J, Wang Y, Huang Y*, Yu J*. Functional screenreveals essential roles of miR-27a/24 in differentiation of embryonic stemcells. EMBO J. 2015 Feb 3;34(3):361-78

9.Ma Y†, Wang B†, Jiang F†, Wang D†, Liu H, Yan Y, Dong H, Wang F, Gong B, Zhu Y, DongL, Yin H, Zhang Z, Zhao H, Wu Z, Zhang J, Zhou J*, Yu J*. A feedback loopconsisting of microRNA-23a/27a and the β-like globin suppressors KLF3 and SP1regulates globin gene expression. Mol Cell Biol. 2013,33(20):3994-4007

10.Fang Wang†, Wei Song†, Hongmei Zhao†, Yanni Ma, Yuxia Li, Di Zhai, JingnanPi,Yanmin Si, Jiayue Xu, Lei Dong, Rui Su, Mengmeng Zhang, Yong Zhu, Xiaoxia Ren,Fei Miao, Wenjie Liu, Feng Li, Junwu Zhang, Aibin He, Ge Shan, Jingyi Hui,Linfang Wang, Jia Yu. The RNA-binding protein QKI5 regulates primary miR-124-1processing via a distal RNA motif during erythropoiesis. Cell Research. 2017 Mar;27(3):416-439

11.Weibin Wang†, Lijun Zhao†, Xueju Wei,Lanlan Wang, Siqi Liu, Yu Yang, Fang Wang, Guotao Sun, Junwu Zhang, Yanni Ma*, Yupei Zhao*, Jia Yu*.MicroRNA-320a promotes 5-FU resistance in human pancreatic cancer cells. Scientific Reports. 2016 Jun 9;6:27641

12.Wei X, Wang W, Wang L, Zhang Y, Zhang X, Chen M,Wang F, Yu J, Ma Y*, Sun G*.MicroRNA-21 induces 5-fluorouracil resistance in human pancreatic cancer cellsby regulating PTEN and PDCD4. Cancer Med. 2016 Feb 10. doi:10.1002/cam4.626

13.Ma YN†, Chen MT†, Wu ZK, Zhao HL, Yu HC, Yu J, Zhang JW. Emodin can induce K562 cells toerythroid differentiation and improve the expression of globin genes. Mol Cell Biochem. 2013, 382(1-2):127-36

14.Y.N. Ma, X.Zhang, H.C. Yu, J.W. Zhang. CTD small phosphatase like 2 (CTDSPL2) can increaseε- and γ-globin gene expression in K562 cells and CD34+ cells derived fromumbilical cord blood. BMC Cell Biology. 2010. 11:75

 15.Y.N. Ma†, X. Zhang†, J.W. Zhang, Xin-Hua Zhang, Rong-Xin Wang.Screening for trans-acting factors involved in the activating or silencing ofg-globin gene during human ontogeny. Biochem. Cell Biol. 2007. 85:347-357

16.X. Zhang†,Y.N. Ma†, J.W. Zhang. Human erythroid progenitors from adultbone marrow and cord blood in optimized liquid culture systems respectivelymaintained adult and neonatal characteristics of globin gene expression. 2007. Biol.Res. 40: 16.41-35