承担科研项目：

        1. 国家重点研发计划，辅助生殖/自然妊娠队列核心家系的全基因组图谱构建及基因组特征变异的系统鉴定，项目编号2021YFC2700601，起止时间：2021年-2024年，参加。

         2. 中国医学科学院创新工程重大协同创新项目，疾病的物质能量代谢转化机制和干预的基础研究，项目编号2021-I2M-1-016，起止时间：2021年-2025年，参加。

在 Hepatology、Molecular Therapy等本领域高水平杂志上以通讯作者发表论文40余篇，其中一篇论文被评估为2012年中国百篇最具影响国际学术论文，2015年荣获第七届“国家卫生计生有突出贡献中青年专家”称号。

      1. ADAR1 Stimulation by IFN-a Downregulates the Expression of MAVS via RNA Editing to Regulate the Anti-HBV Response. Molecular Therapy, 2021;29(3):1335-1348. https://doi.org/10.1016/j.ymthe.2020.11.031

      2. PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats. Neurobiology of Disease, 2019; 121:274–285. https://doi.org/10.1016/j.nbd.2018.10.011

      3. Genetic Variation in STAT4 Predicts Response to Interferon-a Therapy for Hepatitis B e Antigen-Positive Chronic Hepatitis B. HEPATOLOGY, 2016;63( 4):1102-1111. https://doi.org/10.1002/hep.28423

      4. A genome-wide association study identifies polymorphisms in the HLA-DR region associated with non-response to hepatitis B vaccination in Chinese Han populations. Human Molecular Genetics, 2014;23(8):2210-2219. https://doi:10.1093/hmg/ddt586

      5. A missense polymorphism in ATF6 gene is associated with susceptibility to hepatocellular carcinoma probably by altering ATF6 level. Int J Cancer, 2014; 135:61–68. https://doi:10.1002/ijc.28649

      6. Polymorphisms in the VEGFA promoter are associated with susceptibility to hepatocellular carcinoma by altering promoter activity. Int J Cancer, 2013;133(5):1085-1093. https://doi:10.1002/ijc.28109

      7. Targeted genomic sequencing identifies PRRT2 mutations as a cause of paroxysmal kinesigenic choreoathetosis. J Med Genet, 2012;49:76-78. https://doi: 10.1136/jmedgenet-2011-100635

      8. Polymorphisms in ADAR1 gene affect response to interferon alpha based therapy for chronic hepatitis B in Han Chinese. Antiviral Research, 2012;94:272–275. http://doi.10.1016/j.antiviral.2012.03.004

      9. Evaluation of susceptibility locus for response to interferon-α based therapy in chronic hepatitis B patients in Chinese. Antiviral Research, 2012;93:297-300. http://doi:10.1016/j.antiviral.2011.12.009