先后承担多项国家级及省部级研究课题，主要承担课题如下：

1.国家重点研发计划课题，2016YFC0905400，肺癌精准化防诊治模式和规范化临床应用方案研究。

2.国家重点研发计划，2016YFC0905403，生物标志物谱指导的肺癌精准预后判断和真实世界大数据研究。

3.国家高技术研究发展计划，2012AA02A207，肺癌和乳腺癌的“组学”研究。

4.首都临床特色应用研究，Z151100004015188，临床Ⅰa期周围型非小细胞肺癌外科治疗的术式改进及应用。

5.中央级公益性科研院所基本科研业务费，2018PT32033，肺癌微创治疗关键技术开发、优化及集成的研究。

(1) Shugeng Gao; Ning Li; Shunyu Gao; Qi Xue;Jianming Ying; Shuhang Wang;Xiuli Tao; Jun Zhao; Yousheng Mao; Bing Wang; KangShao; Wendong Lei; Dali Wang; Fang Lv; Liang Zhao; Fan Zhang; Ziran Zhao; KaiSu; Fengwei Tan; Yibo Gao; Nan Sun; Dawei Wu; Yue Yu; Yun Ling; Zhijie Wang;Chunjian Duan; Wei Tang; Lei Zhang; Shun He; Ning Wu; Jie Wang; Jie He. NeoadjuvantPD-1 inhibitor (Sintilimab) in Non-Small Cell Lung Cancer. Journal of Thoracic Oncology. 2020;15(5):816 - 826.  

(2) Ruochuan Zang, Ju-Fang Shi , Toni E Lerut, Le Wang, Chia-Chuan Liu, Alessandro Brunelli, René Horsleben Petersen, Calvin Sze Hang Ng, Eric Lim, Shugeng Gao. Ten-year  Trends of  Clinicopathologic  Features  and Surgical Treatment of Lung Cancer in China. Ann Thorac Surg. 2020;109(2):389-395.

(3)Weihua Li, Tian Qiu, Yun Ling, Shugeng Gao, andJianming Ying. Subjecting appropriate lung adenocarcinoma samples tonext-generation sequencing-based molecular testing: challenges and possible solutions.Mol Oncol. 2018, 12(5): 677–689.

(4)Fang Lv , Fan Zhang, Zheng Wang, Shugeng Gao. Minimally invasive McKeown esophagectomy with two-field lymph node dissection and manual cervical esophagogastric anastomosis. J Thorac Dis. 2019;11(7):3175-3179.

(5) Shugeng Gao, Jiagen Li, Xiaoli Feng, Susheng Shi,and Jie He. Characteristics and Surgical Outcomes for Primary Malignant Melanoma of the Esophagus. Sci Rep. 2016, 6: 23804.

(6) Peng Song, Lei Guo, Wenbin Li, Fan Zhang, JianmingYing, and Shugeng Gao. Clinicopathologic correlation with expression of PD-L1 on both tumor cells and tumor-infiltrating immune cells in patients withnon-small cell lung cancer. J Immunother. 2019, 42(1): 23–28.

(7) Wenbin Li, Peng Song, Lei Guo, Xiuyun Liu,Changyuan Guo, Jianming Ying, and Shugeng Gao. Clinical significance of ≥ 50% PD‐L1 expression with theSP263 monoclonal antibody in non‐small cell lung cancerpatients. Thorac Cancer. 2019, 10(2): 175–182.

(8) Bin Qiu, Feiyue Feng, and Shugeng Gao. Partial esophagogastrostomy with esophagogastric anastomosis below the aortic arch incardiac carcinoma: characteristics and treatment of postoperative anastomoticleakage. J Thorac Dis. 2015, 7(11): 1994–2002.

(9) Yihebali Chi, Shugeng Gao, Feng Du, Jin-wanWang, Wen-chang Jiang, Yong-kun Sun, Yan Song, Jie He. Diagnosis, treatment, andprognosis of bronchopulmonary carcinoid: an analysis of 74 patients. AnticancerDrugs. 2016, 27(1): 54-9.

(10) Yushun Gao, Bing Wang, and Shugeng Gao. BRD7Acts as a Tumor Suppressor Gene in Lung Adenocarcinoma. PLoS One. 2016, 11(8):e0156701.

(11) Kang Shao, Yalong Wang, Qi Xue, Juwei Mu, Yushun Gao, Yonggang Wang, Bingzhi Wang, Lina Zhou, Shugeng Gao. Clinicopathological features and prognosis of ciliated muconodular papillary tumor. J Cardiothorac Surg. 2019;14(1):143.

(12) Bin Qiu, Xiaozheng Kang, Ke-Neng Chen, Jian Hu, Jian Li, Liping Zeng, Elliott J Fegelman, Michael L Schwiers, Erin E Creedon, Jason R Waggoner, Ding Ding, Tengfei Yang , Shugeng Gao. Clinical outcomes following an initial experience with a novel powered vascular stapler in video-assisted thoracoscopic lobectomies: results of a Chinese multi-center study. J Thorac Dis. 2019;11(5):1973-1979.

(13) Peng Song , Fanshuang Zhang , Yan Li , Guangjian Yang , Wenbin Li , Jianming Ying , Shugeng Gao. Concomitant TP53 mutations with response to crizotinib treatment in patients with ALK-rearranged non-small-cell lung cancer. Cancer Med. 2019;8(4):1551-1557.

(14) Jiagen Li, Bin Qiu, Marco Scarci, Gaetano Rocco, Shugeng Gao. Uniportal video-assisted thoracic surgery could reduce postoperative thorax drainage for lung cancer patients. Thorac Cancer. 2019;10(6):1334-1339.

(15) Lei Guo, Peng Song, Xuemin Xue, Changyuan Guo, Liankui Han, Qing Fang, Jianming Ying, Shugeng Gao, Wenbin Li. Variation of Programmed Death Ligand 1 Expression After Platinum-based Neoadjuvant Chemotherapy in Lung Cancer. J Immunother. 2019;42(6):215-220.

(16) Peng Song, Ruochuan Zang, Lei Liu, Xiayimaier Dan, Shugeng Gao. Long-term outcomes and prognostic factors of patients with surgically treated pulmonary atypical carcinoid tumors: our institutional experience with 68 patients.J Thorac Dis. 2018;10(7):4204-4211.

(17)Jun Zhao, Jiagen Li, Ning Li, Shugeng Gao. Clinical significance of skipping mediastinal lymph node metastasis in N2 non-small cell lung cancer. J Thorac Dis. 2018;10(3):1683-1688.

(18)Liangze Zhang, Shugeng Gao, Jie He. The role of maintenance therapy in the treatment of elderly non-small-cell lung cancer patients: a meta-analysis of randomized controlled trials. Drug Des Devel Ther. 2017;11:3435-3440.

(19)Bin Qiu, Wanpu Yan, Keneng Chen, Xiangning Fu, Jian Hu, Shugeng Gao, Susan Knippenberg, Michael Schwiers, Edmund Kassis, Tengfei Yang. A multi-center evaluation of a powered surgical stapler in video-assisted thoracoscopic lung resection procedures in China. J Thorac Dis. 2016;8(5):1007-13.

(20)Liangze Zhang, Shugeng Gao. Systematic Review and Meta-analysis of Atrial Fibrillation Prophylaxis After Lung Surgery. J Cardiovasc Pharmacol. 2016;67(4):351-7.

(21)Shugeng Gao, Yalong Wang, Qi Xue, Juwei Mu, Yushun Gao, Fengwei Tan, Yousheng Mao, Dali Wang, Jun Zhao, Yin Li, Jie He. Esophageal Squamous Cell Carcinoma Involving the Lip, Back and Hip. J Thorac Oncol. 2019;14(9):1672-1674.

(22)Peng Song, Jiagen Li, Qingrui Zhang, Shugeng Gao. Ultrathin endoscopy versus computed tomography in the detection of anastomotic leak in the early period after esophagectomy. Surg Oncol. 2020 Mar;32:30-34.

(23)Bin Qiu, Ying Ji, Huayu He, Jun Zhao, Qi Xue, Shugeng Gao. Three-dimensional reconstruction/personalized three-dimensional printed model for thoracoscopic anatomical partial-lobectomy in stage I lung cancer: a retrospective study. Transl Lung Cancer Res. 2020;9(4):1235-1246.

(24)Yun Ling, Ning Li, Lin Li, Changyuan Guo, Jiacong Wei, Pei Yuan, Fengwei Tan, Xiuli Tao, Shuhang Wang, Zhijie Wang, Ning Wu, Jie Wang, Jianming Ying, Shugeng Gao, Jie He. Different pathologic responses to neoadjuvant anti-PD-1 in primary squamous lung cancer and regional lymph nodes. NPJ Precis Oncol. 2020;4(1):32.

(25)Wei Guo, Qilin Huai, Guochao Zhang, Lei Guo, Peng Song, Xuemin Xue, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He. Elevated Heterogeneous Nuclear Ribonucleoprotein C Expression Correlates With Poor Prognosis in Patients With Surgically Resected Lung Adenocarcinoma. Front Oncol. 2021;10:598437.

(26)Ying Ji, Guangyu Bai, Bin Qiu, Liang Zhao, Jing Zhou, Qi Xue, Shugeng Gao. The surgical management of early-stage lung adenocarcinoma: is wedge resection effective? J Thorac Dis. 2021;13(4):2137-2147.

(27)Wei Guo, Fengwei Tan, Qilin Huai, Zhen Wang, Fei Shao, Guochao Zhang, Zhenlin Yang, Renda Li, Qi Xue, Shugeng Gao, Jie He. Comprehensive Analysis of PD-L1 Expression, Immune Infiltrates, and m6A RNA Methylation Regulators in Esophageal Squamous Cell Carcinoma. Front Immunol. 2021;12:669750.

(28)Bin Qiu, Feiyue Feng, Shugeng Gao. Partial esophagogastrostomy with esophagogastric anastomosis below the aortic arch in cardiac carcinoma: characteristics and treatment of postoperative anastomotic leakage. J Thorac Dis. 2015;7(11):1994-2002.