作为项目负责人先后主持过2项国家863项目，1项国家自然科学基金重大研究计划项目，及多项国家自然科学基金面上项目。

代表作（*通讯作者）：

1.       Meihong Chen, Lishu Zhang, Hong-Yan Zhang, Xiahui Xiong, Bo Wang, QuanDu, Bing Lu, Claes Wahlestedt, Zicai Liang. A universal plasmid libraryencoding all permutations of small interfering RNA. Proceedings of  National Academyof  Sciences of the United States ofAmerica 2005; vol 102; no. 7; 2356-2361.

2.       CuiqingFan, Lin Dong, Ning Zhu, Yuan Xiong, Jiewen Zhang, Le Wang, Yan Shen, XiaoyinZhang, Meihong Chen*. Isolation ofsiRNA target by biotinylated siRNA reveals that human CCDC12 promotes earlyerythroid differentiation. LeukemiaResearch 2012;36:779-783.

3.       YuanXiong, Cuiqing Fan, Lijuan Kong, Lin Dong, Ning Zhu, Jiewen Zhang, Le Wang, TaoQin, Yan Shen, Meihong Chen*. AnnexinII receptor induces apoptosis independent of Annexin II. Apoptosis 2013;18:925-939.

4.       Jiewen Zhang, Lijuan Kong, Sichao Guo, Mengmeng Bu, Qian Guo, Yuan Xiong,Ning Zhu, Chuan Qiu, Xuejing Yan, Qian Chen, Hongfei Zhang, Junling Zhuang, QiongWang, Samuel S. Zhang, Yan Shen and Meihong Chen*. hnRNPs and ELAVL1cooperate with uORFs to inhibit protein translation. Nucleic Acids Research 2017;45(5):2849-2864.

获得授权专利：

1.“RandomisedDNA libraries and double-stranded RNA libraries, use and method of productionthereof”，2007年获得澳大利亚发明专利授权（第4发明人）。

2.“用于诱导白血病细胞分化的小分子RNA及其应用”，2012年获得中国发明专利授权（第1发明人）。