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贾美荣、博士生导师、课题组长、北京市科技新星。山东大学制药工程学士、山东大学药物化学硕士、美国Iowa State University生物化学 博士、美国University of California, Davis 博士后。兼任《Chinese Journal of Natural Medicines》,《Physical Science & Biophysics Journal》和《InternationalJournal of Analytical and Bioanalytical Methods》青年编委, 《Molecular Plant》科学编辑。2021年作为中国医学科学院“高层次引进人才”,到北京协和医学院药物研究所工作,任课题组长。迄今在ACSCatalysis, Metabolic Engineering, PNAS, Nature Communications 等国际著名期刊发表研究论文和论著近30篇。
贾美荣 课题组长 Iowa State University 博士, University of California, Davis, 博士后
李静一 助理研究员 中国科学院植物研究所博士、博士后
在读研究生
李玉姣(2021级博士)
梁苗苗(2022级博士)
谢军(2023级博士)
孙鑫(2021级硕士)
李萌(2022级硕士)
梅一婷(2022级硕士)
张浩彬(2023级硕士)
邹洋(2023级硕士)
中国医学科学院“高层次引进人才”启动经费
中国医学科学院药物研究所 “独立课题组长” 人才启动经费
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中国医学科学院“高层次引进人才”启动经费
中国医学科学院药物研究所人才启动经费
代表性论文:
1. Furanoditerpenoid biosynthesis in the bioenergycrop switchgrass is catalyzed by an alternate metabolic pathway. Muchlinski A#,Jia M#,Tiedge K, Fell J, Pelot K, Chew L, Davisson D, Chen Y, Siegel J, Lovell J,Zerbe P. Preprint, 2021, DOI: 10.1101/2021.03.30.437764.
2. Switching on a nontraditional enzymaticbase–deprotonation by serine in the ent-kaurene synthase from Bradyrhizobiumjaponicum. Jia M#, Zhang Y#, Siegel JB,Tantillo DJ, Peters RJ. ACS Catal., 2019, 9, 8867.
3. Changing face: A key residue for the addition ofwater by sclareol synthase. Jia M,O’Brien TE, Zhang Y, Siegel JB, Tantillo DJ, Peters RJ. ACS Catal., 2018, 8:3133.
4. Combinatorial biosynthesis and the basis forsubstrate promiscuity in class I diterpene synthases. Jia M, Mishra S, Tufts S, Jernigan R, Peters RJ. Metab Eng.,2019, 55:44.
5. Extreme promiscuity of a bacterial and a plantditerpene synthase enables combinatorial biosynthesis. Jia M, Potter KC, Peters RJ. Metab Eng., 2016, 37:24.
6. Jasmonic acid transport in wound-induced systemicimmunity. Jia M. MolecularPlant, 2020, 13:1673. Editor’s highlight.
7. A pair of residues that interactively affectditerpene synthase product outcome. JiaM, Zhou K, Tufts S, Schulte S, Peters RJ. ACS Chem. Biol., 2017,12:862.
8. Extending a single residue switch forabbreviating catalysis in plant ent-kaurene synthases. Jia M, Peters RJ. Frontiers inPlant Science, 2016, 7:1765.
9. Cis or trans with class II diterpene cyclases. Jia M, Peters RJ. Organic &Biomolecular Chemistry, 2017, 15:3158.
10. Probing the promiscuity of ent-kaureneoxidases via combinatorial biosynthesis. Mafu S, Jia M, Zi J, Morrone D, Wu Y, Xu M, Hillwig ML,Peters RJ. Proc Natl Acad Sci U S A, 2016, 113:2526.
11. Premutilin synthase: Ring rearrangement by aClass II diterpene cyclase. Xu M, JiaM, Hong YJ, Yin X, Tantillo DJ, Proteau PJ, Peters RJ. Org Lett., 2018,20:1200.
12. Product rearrangement from altering a singleresidue in the rice syn-copalyl diphosphate synthase. Potter KC, Jia M, Hong YJ, TantilloDJ, Peters RJ. Org Lett., 2016, 18:1060.
13. Genome of Tripterygium wilfordii andidentification of cytochrome P450 involved in triptolide biosynthesis. Tu L, SuP, Zhang Z, Gao L, Wang J, Hu T, Zhou J, Zhang Y, Zhao Y, Liu Y, Song Y, TongY, Lu Y, Yang J, Xu C, Jia M,Peters RJ, Huang L, Gao W. Nat Commun.,2020, 11:971.
14. The analgesic activity of Bestatin as a potentAPN inhibitor. Jia M, Wei T,Xu W. Front Neurosci., 2010, 4:1.
15. Novel aminopeptidase N (APN/CD13) inhibitorsderived from chloramphenicol amine. JiaM, Yang K, Fang H, Xu Y, Sun S, Su L, Xu W. Bioorg Med Chem.,2011, 19:5190.
专著:
Molecular Pharmacognosy, second edition. 编者,chapters 7 and 9,Springer,2019.
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