赫捷院士是我国肺癌、食管癌等胸部肿瘤外科治疗的领军者和规范化综合诊疗的推动者，是我国最早创立肿瘤遗传资源库和转化研究实验室的临床肿瘤专家之一。主持国家重大公共卫生专项、国家重点研发计划、高技术研究发展计划、科技支撑计划等多项国家级重大项目。作为通讯作者在CA: A Cancer Journal for Clinicians, Nature Genetics, Gut, Lancet Glob Health, Signal Transduction and Targeted Therapy, Journal of Thoracic Oncology, Clinical Cancer Research等国际权威学术期刊发表论文百余篇，获得国内外发明专利10余项。牵头制定我国《食管癌规范化诊治指南》、《肺癌规范化诊治指南》、《食管癌诊断标准》、《肺癌诊断标准》等行业标准，主编国家级医学专业规划教材《肿瘤学》、《临床肿瘤学》、《食管癌》、《食管癌微创外科手术教程》等学术专著十余部，以第一完成人领衔的“食管癌规范化治疗关键技术的研究及应用推广”成果荣获国家科技进步一等奖。曾获高等学校科学研究优秀成果奖一等奖、中华医学科技奖一等奖、全国优秀科技工作者、卫生部有突出贡献中青年专家、“全国师德楷模”等荣誉称号。

       以通讯作者发表的代表性论著：

1. 1. Gao S, Li N, Gao S, Xue Q, Ying J, Wang S, Tao X, Zhao J, Mao Y, Wang B, Shao K,Lei W, Wang D, Lv F, Zhao L, Zhang F, Zhao Z, Su K, Tan F, Gao Y, Sun N, Wu D,Yu Y, Ling Y, Wang Z, Duan C, Tang W, Zhang L, He S, Wu N, Wang J, He J. Neoadjuvant PD-1 inhibitor (Sintilimab) in NSCLC. J Thorac Oncol. 2020 Feb 6:S1556-0864(20)30057-5;
2. 2. Chen H, Li N, Ren J, Feng X, Lyu Z, Wei L, Li X, Guo L, Zheng Z, Zou S, Zhang Y, LiJ, Zhang K, Chen W, Dai M, He J, group of Cancer Screening Program in Urban China(CanSPUC). Participation and yield of a population-based colorectal cancer screening programme in China. Gut. 2019 Aug;68(8):1450-1457;
3. 3. Chen W, Xia C, Zheng R, Zhou M, Lin C, Zeng H, Zhang S, Wang L, Yang Z, Sun K, Li H,Brown MD, Islami F, Bray F, Jemal A, He J. Disparities by province, age, and sex in site-specific cancer burden attributable to 23 potentially modifiable risk factors in China: a comparative risk assessment. Lancet Glob Health. 2019Feb;7(2):e257-e269;
4. 4. Zeng H, Chen W, Zheng R, Zhang S, Ji JS, Zou X, Xia C, Sun K, Yang Z, Li H, Wang N,Han R, Liu S, Li H, Mu H, He Y, Xu Y, Fu Z, Zhou Y, Jiang J, Yang Y, Chen J,Wei K, Fan D, Wang J, Fu F, Zhao D, Song G, Chen J, Jiang C, Zhou X, Gu X, JinF, Li Q, Li Y, Wu T, Yan C, Dong J, Hua Z, Baade P, Bray F, Jemal A, Yu XQ, He J. Changing cancer survival in China during 2003-15: a pooled analysis of 17 population-based cancer registries. Lancet Glob Health. 2018 May;6(5):e555-e567;
5. 5.  Chen W, Zheng R, Baade PD, Zhang S, Zeng H, Bray F, Jemal A, Yu XQ, He J. Cancer statistics in China, 2015. CA Cancer J Clin. 2016 Mar-Apr;66(2):115-32;
6. 6. Gao YB, Chen ZL, Li JG, Hu XD, Shi XJ, Sun ZM, Zhang F, Zhao ZR, Li ZT,Liu ZY, Zhao YD, Sun J, Zhou CC, Yao R, Wang SY, Wang P, Sun N, Zhang BH, DongJS, Yu Y, Luo M, Feng XL, Shi SS, Zhou F, Tan FW, Qiu B, Li N, Shao K, ZhangLJ, Zhang LJ, Xue Q, Gao SG, He J.Genetic landscape of esophageal squamous cell carcinoma. Nature Genetics. 2014,46(10):1097-1102;
7. 7. Li JG, Chen ZL, Tian LQ, Zhou CC, He MY, GaoYB, Wang SY, Zhou F, Shi SS, Feng XL, Sun N, Liu ZY, Skogerboe G, Dong JS, YaoR, Zhao YD, Sun J, Zhang BH, Yu Y, Shi XJ, Luo M, Shao K, Li N, Qiu B, Tan FW,Chen RS, He J. LncRNA profile study reveals a three-lncRNA signature associated with the survival of patients with oesophageal squamous cell carcinoma. Gut. 2014, 63(11):1700-1710;
8. 8. Sun N, Chen Z, TanF, Zhang B, Yao R, Zhou C, Li J, Gao Y, Liu Z, Tan X, Zhou F, He M, Shao K, Li N,Qiu B, Sun J, Yu Y, Wang S, Zhao Y, Shi X, He J. Isocitrate Dehydrogenase 1 Is a Novel Plasma Biomarker for the Diagnosis of Non–Small Cell Lung Cancer. Clinical Cancer Research. 2013 Sep 15;19(18):5136-45.