王琳芳：教授

宋伟：研究员

缪时英：教授（返聘）  

刘长征：副研究员                    

李凯：副研究员                                                            

卢艳：技术员

博士研究生：邹定峰 ，李梦真

直博研究生：李鹏宇，阿曼妮萨，邙新雨，许富

硕士研究生：苏路瑛，柳俊，汤洁琳，余志鑫

中国医学科学院医学与健康科技创新工程项目：肝癌精准诊疗关键技术的研究与应用        2021.10-2025.12          课题负责人            160万

中国医学科学院医学与健康科技创新工程项目：肝癌精准诊疗关键技术的研究与应用       2021.10-2025.12   课题负责人            160万

全部著作：

一．著作：

王琳芳，杨克恭，2001年7月，医学分子生物学原理，北京，高等教育出版社，1012页

王琳芳，杨克恭，1998年6月，蛋白质与核酸，北京，北京医科大学 中国协和医科大学联合出版社，478页

二．译著：

兹巴尔斯基，伊万诺夫，玛尔达什夫，1953年，生物化学，王琳芳译，北京，人民卫生出版社，557页

三.     论著：

1. Hong Zhao, Yalan Lu, Rong Huang, jianming ying, Xingchen Li, Tao Jiao, Lei Guo, Haitao Zhou, Han Wang, Amannisa Tuersuntuonebit, Jianmei Liu, Qichen Chen, Yanhong Wang, Luying Su, Changyuan Guo, Fu Xu, Ziyi Wang, Yan Lu, Kai Li, Junbo Liang, Zhen Huang, Xiao Chen, Jinjie Yao, Hanjie Hu, Xiaowen Cheng, Yufeng Wan, Xinyan Chen, Ning Zhang, Shiying Miao, Jianqiang Cai, Linfang Wang, Changzheng Liu, and Wei.RING finger 138 deregulation distorts NF-кB signaling and facilities colitis switch to aggressive malignancy.Signal Transduction and Targeted Therapy.(accepted)

2. Kai Li, Jiayue Xu, Yanyun Luo, Dingfeng Zou, Ruiqin Han, Shunshun Zhong, Qing Zhao, Xinyu Mang, Mengzhen Li, Yanmin Si, Yan Lu, Pengyu Li, Cheng Jin, Zhipeng Wang, Fang Wang, Shiying Miao, Bo Wen, Linfang Wang, Yanni Ma, Jia Yu, and Wei Song(2021). Panoramic transcriptome analysis and functional screening of long non-coding RNAs in mouse spermatogenesis. Genome Research, 2021, 31(1)：13-26.

3. Junbo Liang, Yanchi Zhou, Ning Zhang, Dingding Wang, Xiaowen Cheng, Kai Li, Rong Huang, Yan Lu, Hailong Wang, Deqiang Han, Wei Wu, Meng Han, Shiying Miao, Linfang Wang, Hong Zhao,Wei Song(2021）. The phosphorylation of the Smad2/3 linker region by Nemo-like kinase regulates TGF-β signaling. J Biol Chem. 2021, 296: 100512.

4. Xiaojuan Wang, Fan Wu, Han Wang, Xiaoyuan Duan, Rong Huang, Amannisa Tuersuntuoheti, Luying Su,Shida Yan, Yuechao Zhao, Yan Lu, Kai Li, Jinjie Yao, Zhiwen Luo, Lei Guo, Jianmei Liu, Xiao Chen, Yalan Lu, Hanjie Hu, Xingchen Li, Mandula Bao, Xinyu Bi, Boyu Du, Shiying Miao, Jianqiang Cai, Linfang Wang, Haitao Zhou, Jianming Ying, Wei Song and Hong Zhao（2020）. PDCD6 Cooperates with C-Raf to Facilitate Colorectal Cancer Progression via Raf/MEK/ERK Activation. J Exp Clin Cancer Res.2020, 39: 147.

5. Yuechao Zhao, Yiran Li, Jie Sheng,Fan Wu, Kai Li, Rong Huang, Xiaojuan Wang, Tao Jiao, Xin Guan,Yan Lu, XiaoChen, Zhiwen Luo, Yanchi Zhou, Hanjie Hu, Wenjie Liu, Boyu Du, Shiying Miao,Jianqiang Cai, Linfang Wang, Hong Zhao, Jianming Ying, Xinyu Bi, Wei Song(2019). P53-R273Hmutation enhances colorectal cancer stemness through regulating specificlncRNAs.  Journal of Experimental & Clinical Cancer Research, 2019, 38:379

6. Kai Li, Shunshun Zhong, YanyunLuo, Dingfeng Zou, Mengzhen Li, Yahui Li, Yan Lu, Shiying Miao,Linfang Wang andWei Song(2019). A long noncoding RNA binding to QKI-5 regulates germ cell apoptosisvia p38 MAPK signaling pathway. Cell Death and Disease. 2019,10:699

7. Xin Zhang, Wenjie Liu, YuechaoZhao, Changjun Wang, Hongge Ju , Xiaohui Zhang, Shiying Miao, Linfang Wang, Qiang Sunand Wei Song(2018). Rhomboid domain containing 1 promotes breast cancer progression by regulating thep-Akt and CDK2 expression. Cell Communication and Signaling. 2018,16:65.

8. Yalan Lu, Deqiang Han, Wenjie Liu,Rong Huang, Jinhuan Ou, Xiaoqiao Chen, Xizhe Zhang, XuezhiWang, Shijun Li, LinWang, Changzheng Liu, Shiying Miao, Linfang Wang, Changwu Ma and Wei Song(2018). RNF138 confers cisplatin resistance in gastric cancer cells via activating Chk1 signaling pathway.  Cancer Biology andTherapy. 2018.1480293

9. Mengmeng Zhang, Fei Miao, RongHuang, Wenjie Liu, Yuechao Zhao, Tao Jiao, Yalan Lu, Fan Wu, Xiaojuan Wang , HanWang, Hong Zhao, Hongge Juc, Shiying Miao, Linfang Wang,  Wei Song (2018). RHBDD1 promotes colorectal cancer metastasis through the Wntsignaling pathway and its downstream target ZEB1. Journalof Journal of Experimental & Clinical Cancer Research  37:22-35

10. Fang Wang, Wei Song, HongmeiZhao, Yanni Ma, Yuxia Li, Di Zhai, Jingnan Pi, Yanmin Si, Jiayue Xu, Lei Dong,Rui Su, Mengmeng Zhang, Yong Zhu, Xiaoxia Ren, Fei Miao, Wenjie Liu, Feng Li, JunwuZhang, Aibin He, Ge Shan, Jingyi Hui, Linfang Wang, Jia Yu. The RNA-bindingprotein QKI5 regulates primary miR-124-1 processing via a distal RNA motifduring erythropoiesis. Cell Research, 2017, 27(3): 416-439.

11. 赵晴, 韩睿钦, 王琳芳, 宋伟.（2017） 一种利用吖啶橙染色快速鉴定重力密度沉降中生精细胞类型的方法 基础医学与临床

12. Longchang Xu, Yalan Lu, DeqiangHan, Rongyan Yao, Han Wang, Shunshun Zhong, Yanyun Luo, Ruiqin Han, Kai Li, Jun Fu, ShudongZong, Shiying Miao, Wei Song and Linfang Wang. Rnf138 promotes theproliferation of spermatogonia in juvenile male mice. Cell Death and Disease(2017) 8, e2795

13. Fei Miao, Mengmeng Zhang, YuechaoZhao, Xiaolu Li, Rongyan Yao, Fan Wu, Rong Huang, Kai Li, Shiying Miao,Changwu Ma, Hongge Ju, Wei Song, linfang Wang20(17). RHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer. Oncotarget,, Vol. 8, (No.15), pp: 25251-25260.

14. 王任先，李凯，姚荣彦，缪时英，王琳芳，宋伟.(2016) 过表达TRIM69抑制内源c-Jun的蛋白表达.

15. Ruiqin Han, Qing Zhao, Shudong Zong,Shiying Miao, Wei Song, Lin Fang Wang. (2016) A Novel TRIM Family Member,Trim69, Regulates Zebrafish Development Through p53- Mediated Apoptosis. MolecularReproduction & Development 82:1-13

16. Jun Fu, Rongyan Yao, Yanyun Luo,Dantong Yang, Yang Cao, Yi Qiu, Wei Song, Shiying Miao,Yiqun Gu & Linfang Wang. (2016) Anti-GAPDHS antibodies: a biomarker ofimmune.Cell Tissue Res 364:199–207

17. Deqiang Han, Junbo Liang, YalanLu, Longchang Xu, Shiying Miao, Lin-Yu Lu,Wei Song, LinfangWang (2016) Ubiquitylation of Rad51d Mediated by E3 LigaseRnf138 Promotes the Homologous Recombination Repair Pathway. PLOS ONE11(5):e0155476.

18. Ruiqin Han,, Renxian Wang,, QingZhao, Yongqing Han, Shudong Zong, Shiying Miao, Wei Song, Linfang Wang（2016）.  Trim69 regulates zebrafish brain developmentby ap-1 pathway. Scientific Reports 6:24034

19. Yanchuan Li, Hui Wang, XiaofeiZhou, Xiaoping Xie, Xiang Chen, Zuliang Jie, Qiang Zou, Hongbo Hu, Lele Zhu,Xuhong Cheng, Hans D Brightbill, Lawren C. Wu, Linfang Wang & Shao-Cong Sun. (2016)  Cellintrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immuneand autoimmune responses. Scientific Reports 6:22115

20. Jun Fu, Rongyan Yao. Yanyun Luo,Dantong Yang, Yang Cao, Yi Qiu, Wei Song,Shiying Miao, Yiqun Gu & LinfangWang.(2016) Immune Inrertility Should Be Positively DiagnosedUUsing an Accurate Method by Monitoring the Level of Anti-ACTL7a Antibody.Scientific Reports 6:22844

21. Wei Song,Wenjie Liu,HongZhao,Shangze Li,Xin Guan,Jianming Ying,Yefan Zhang, iaoxia Ren,FeiMiao,Mengmeng Zhang,Wenming Wu,Jun Fu,Junbo Liang,Wei Wu,Changzheng Liu,JiaYu,Shudong Zong,Shiying Miao,Xiaodong Zhang,Linfang Wang. (2015) RhomboidDomain Containing 1  (RHBDD1)  Promotes Colorectal Cancer Growth through Activation of the EGFR SignalingPathway. Nature Communication 6:8022,1-13 | DOI: 10.1038/ncomms9022

22. 吴为 李琴山 宋伟 缪时英 王琳芳(2014). 串联亲和纯化技术筛选Bat3的相互作用蛋白质.中国医科院学报 35（4）：423-426

23. 梁俊波 缪时英 王琳芳（2014）. 利用串联亲和纯化结合质谱分析分离和鉴定与蛋白激酶NLK结合的蛋白复合物组分. 医学研究杂志 43(7):19-22

24. 李芸侨 李尚泽 宋伟 王任先 张晓东 王琳芳.(2014) 人结直肠癌细胞Drosha基因敲除细胞模型的构建. 医学研究杂志 43(6):21-24

25. Yang Li, Han Wu, Wei Wu,Wei Zhuo, Weixiao Liu, Yixiao Zhang, Minzhang Cheng, Ye-Guang Chen, Ning Gao,Hongtao Yu, Linfang Wang, Wei Li, Maojun Yang. (2014). Structural insights intothe TRIM family of ubiquitin E3 ligases. Cell Research 24(6):762-765

26. Shan Lu, Renxian Wang, CongliCai, Junbo Liang, Longchang Xu, Shiying Miao, Linfang Wang, Wei Song(2014). Small Kinetochore Associated Protein (SKAP) promotes UV-induced cell apoptosisthrough negatively regulating Pre-mRNA processing Factor 19 (Prp19). PLoS One9(4)：e92712.

27. Zebin Huang, Shangze Li, WeiSong, Xin Li, Qinshan Li, Zeyan Zhang, Yongqing Han, Xiaodong Zhang, ShiyingMiao, Runlei Du, Linfang Wang（2013）Lysine-SpecificDemethylase 1 (LSD1/KDM1A) Contributesto Colorectal Tumorigenesis via Activation of the Wnt/B-Catenin Pathway byDown-Regulating Dickkopf-1 (DKK1). PLoS One 8(7)：e70077

28. Xiaoxia Ren, Wei Song , WenjieLiu, Xin Guan, Fei Miao, Shiying Miao, Linfang Wang. (2013). Rhomboid domaincontaining 1 inhibits cell apoptosis by upregulating AP-1 activity and itsdownstream target Bcl-3. FEBS Letters 587: 1793-1798

29. 宋伟 狄茜 缪时英 王琳芳（2013）HSD1与微管蛋白在生精细胞中的定位关系研究. 医学研究杂志 42(6):20-22

30. 付俊 缪时英 宋伟. 人精子肌动蛋白样蛋白7a在大肠杆菌系统的表达纯化及多克隆抗体制备.细胞与分子免疫学杂志29(5):507-510

31. Min-xian Qian, Ye Pang, Cui-hua Liu,Kousuke Haratake, Bo-yu Du, Dan-yang Ji, Guang-fei Wang,Qian-qian Zhu, WeiSong,Yadong Yu, Xiao-xu Zhang, Hai-tao Huang, Shi-ying Miao, Lian-bin Chen,Zi-hui Zhang, Ya-nan Liang, Shan Liu, Hwangho Cha, Dong Yang, Yonggong Zhai,Takuo Komatsu, Fuminori Tsuruta，Hai-tao Li, Cheng Cao, Wei Li,Guo-hong Li, Yi-fan Cheng, Tomoki Chiba, Lin-fang Wang, Alfred L. Goldberg, YanShen,and Xiao-bo Qiu. Acetylation-Mediated proteasomal degradation of corehistones during DNA repair and spermatogenesis(2013). Cell 153:1012-1024

32. 宋伟 陈迎春 缪时英 王琳芳（2013）.HSD1蛋白在精子发生过程中的空间特异性表达. 基础医学与临床33(3):325-329

33. 宋伟 胡廷徽 缪时英 王琳芳（2013）睾丸高表达蛋白质HSD13调节CHO细胞系周期进程. 基础医学与临床33(2):179-183

34. Jun Fu, WeiSong, Shudong Zong, Samuel S. Koide, Shiying Miao,and Linfang Wang（2013） Dynamicalterations in the expression and localization of ACTL7a during    capacitationin mouse spermatozoa. Fertility and sterility. 99（3）:882-888

35. Xiaolu Li, Wei Zhuo JieYu,Jingpeng Ge, Jinke Gu, Yue Feng, Maojun Yang,,linfangWang and Na Wang（2013）Structure of the nucleotide-binding domain of a dipeptide ABCtransporter reveals a novel iron–sulfur cluster-binding domain. Acta Cryst. D69:256–265

36. 韩永卿 李容 高晋兰 缪时英 王琳芳(2013).人睾丸组织TRIM69蛋白具有催化多聚泛素链形的活性. 基础医学与临床33（1）：77-81

37. Yongqing Han, Rong Li, JinlanGao, Shiying Miao, Linfang Wang(2012). Characterization of human RING fingerprotein TRIM69, a novel testis E3 ubiquitin ligase and its subcellularlocalisation. BBRC 429（1-2）

38. Hong Zhao, Qinshan Li, Jian Wang,xianwei Su, Ka Man Ng, Tian Qiu, Ling Shan, Yun Ling, Linfang Wang, Jian qiangCai, Jianming Ying(2012). Frequent epigenetic silencing of thefolate-metabolising gene cystathionine-beta-synthase in gastrointestinalcancer. PLoS ONE 7(11): e 49683 

39. Wei Wu, Wei Song, Shuchun Li,Songying Ouyang, Kin Lam Fok, Ruiying Diao, Shiying Miao, Hsiao Chang Chan* andLinfang Wang(2012). Regulation of apoptosis by Bat3-enhanced YWK-IIprotein/APLP2 stability. J. Cell Sciences 125(18):4219-4229

40. 关欣 李树春 狄茜 缪时英 王琳芳（2012）小鼠体内生精系统重塑模型的建立. 医学研究杂志41（10）：30-32

41. Jinlan Gao, Xiaolu Li, Yue Feng,Bo Zhang, Shiying Miao Linfang Wang and Na Wang（2012） Purification and crystallization of the ABC-typetransportsubstrate-binding protein OppA from thermoanaerobacter tangcongensis.BBRC 423:45-49 

42. Chunhua Wan, Jun Fu, Yong Wang,Shiying Miao, Wei Song, Linfang Wang(2012), Exosome-Related Multi-PassTransmembrane Protein TSAP6 Is a Target of Rhomboid Protease RHBDD1 InducedProteolysis. . PLoS ONE 7(5): e 37452 

43. Jun Fu, Ph.D. Yong Wang, Ph.D.,Kin Lam Fok, Ph.D., Dantong Yang, Ph.D., Yi Qiu, Hsiao Chang Chan, Ph.D.,Samuel S. Koide,Ph.D., M.D., Shiying Miao, and Linfang Wang(2012). Anti-ACTL7a antibodies: a cause of infertility. Fertilityand Sterility 97(5): 1226-1233 （3.96）

44. Xiaowen Cheng , Junbo Liang , YuTeng , Jun Fu , Shiying Miao , Shudong Zong , Linfang Wang. Nemo-like kinasepromotes etoposide-induced apoptosis of male germ cell-derived GC-1 cells invitro FEBS Letters 586 (2012), pp. 1497-1503

45. Hong Zhao, Jian Wang, YongqingHan, Zhen Huang, Jianming Ying, Xinyu Bi, Jianjun Zhao, Yi Fang, Haitao Zhou,Jianguo Zhou, Zhiyu Li, Yefan Zhang, Xue Yang, Tao Yan , Linfang Wang, MichaelS. Torbenson, Jianqiang Cai(2011). ARID2: A new tumor suppressor gene inhepatocellular carcinoma.  Oncotarget, 2(11):886-892

46. Meng Li, Hong Zhao, XiaosongZhang, Laura D Wood, Robert A Anders, Michael A Choti,Timothy M Pawlik, Hubert D Daniel, Rajesh Kannangai, G Johan A Offerhaus,VictorE Velculescu, Linfang Wang, Shibin Zhou, Bert Vogelstein, Ralph H Hruban, NickPapadopoulos, Jianqiang Cai, Michael S Torbenson, and Kenneth W Kinzler Inactivatingmutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma. Nat Genet. ; 43(9): 828–829

47. 黄泽彬 张泽延 张晓东 缪时英 王琳芳 杜润蕾（2011）非洲爪蟾驱动蛋白样蛋白2靶蛋白C’末端SBP-3Xflag标记的HCT116结直肠癌细胞模型的建立. 中国医学科学院学报33（6）：608-612

48. 程筱雯 梁俊波 缪时英 王琳芳（2011）蛋白激酶Nemo样激酶重组腺病毒载体的构建与鉴定. 中国医学科学院学报33（6）：618-623

49. 付俊 缪时英（2011） 小鼠睾丸曲细精管生精上皮的分离及形态观察. 中国医学科学院学报33（6）：605-607

50. 宋伟 李尚泽 张慧慧 缪时英 王琳芳 张晓东 杜润蕾，（2011）应用改良体细胞敲入技术内源标记跨膜丝氨酸蛋白酶RHBDD1的研究. 医学研究杂志40（11）：21-24

51. Yu Teng,Yong VVang,Jun Fu,XiaowenCheng,Shiying Miao,Linhng Wang. (2011) Cyclin T2∶ A novel miR-15a target gene involved in earlyspermatogenesis. FEBS letters 585:2493-2500

52. Hailong Wang, , Wei Song,*  Tinghui Hu,  Ning Zhang, Shiying Miao,  Shudong Zong,  Linfang Wang*. (2011) Fank1 interacts withJab1 and regulates cell apoptosis via the AP-1 pathway. Cell. Mol. Life Sci.68:2129–2139

53. Jennifer M. Doyle, Jinlan Gao,Jiawei Wang, Maojun Yang and Patrick Ryan Potts. (2010). MAGE-RING ProteinComplexes Comprise a Family of E3 Ubiquitin Ligases. Molecular Cell 39:963-974

54. Ning Zhang, Junbo Liang,Yongqiang Tian, Ligang Yuan, Lan Wu, Shiying Miao, ShudongZong, and Linfang Wang. （2010） Anovel testis specific GTPase serves as a link toproteasome biogenesis: functional characterization of RhoS/RSA-14-44 in spermatogenesis. Mol. Biol. Cell.

55. Yong Wang, Wei Song, ShuchunLi, Xin Guan, Shiying Miao, Shudong Zong, S.S.Koide, Linfang Wang. (2009). Aloss of spermatogenic ability in mouse seminiferous tubules of the GC-1 mRHBDD1knockdown spermatogonia cell line. BMC Cell Biol 10：25

56 .Shuchun Li, YuanQiao, Qian Di, Xiuning Le, Lei Zhang, Xiaosong Zhang, Changyong Zhang, JieCheng, Shudong Zong, S.S.Koide, Shiying Miao and Linfang Wang(2009).  Interaction of SH3P13 and DYDC1 Protein: AGerm Cell Component that Regulates Acrosome Biogenesis during SpermiogenesisEur. J.Cell Biol  88：509-520

57. Rong Li, Xiao-Ling Tang, Shi-YingMiao, Shu-Dong Zong and Lin-Fang Wang.(2009). Regulationof the G2/M phase of the cell cycle by sperm associated antigen 8 (SPAG8)protein. Cell Biochem and Function 27：264-268

58. Yong Wang, Ning Zhang, XiaodongZhang, Shiying Miao, Shudong Zong, S.S.Koide, and Linfang Wang. (2009), ExperimentalImmunologic Infertility Effect of Anti-GAPDH-2 Antibodies on the Fertility ofFemale Mice. Fertility and Sterility  (inpress)

59.宋伟 胡廷徽 陈叙 缪时英 王琳芳.(2009). 睾丸高表达蛋白质HSD-14对小鼠精子发生的影响.医学研究杂志 38（5）：32-36

60.黄海涛 宋伟 缪时英 王琳芳.（2009）.人源Fank1蛋白质FN3结构域多肽的原核表达，纯化及晶体筛选. 医学分子生物学杂志（6（3）1193-196

61.张宁 王勇 陈迎春 吴宁 缪时英 王琳芳.(2008). 睾丸表达新基因HSD-28的克隆及其编码蛋白质的研究. 医学研究杂志 37（12）：1～5

62. Yong Wang, Shuchun Li, Kin LamFok, Xin Guan, Xiaodong Zhang, Shiying Miao, Shudong Zong, S.S.Koide, HsiaoChang Chan, and Linfang Wang. （2008）.  A novelmember of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis.Cellular and Molecular Life Sciences  65(23):3822-9

63. Xu Chen, Tinghui Hu, Gang Liang,Maojun Yang, Shudong Zong, Shiying Miao, Samuel S. Koide and Linfang Wang. （2008）. A novel testis protein RSB-66 interacting with INCA1 (inhibitor ofCdk interacting with cyclin A1). Bioch cell biology 86(4):345-351

64. Xueqian Yin, Songying Ouyang,Wenming Xu, Xiaopeng Zhang, Kin Lam Fok, Hau Yan Wong, Jiaping Zhang, XiaoboQiu,Shiying Miao, Hsiao Chang Chan and Linfang wang . （2007）. YWK-II protein as a novel Go-coupled receptor for MüllerianInhibiting Substance in cell survival. J. Cell Science 120：1521-8

65.王勇 陈轶男 乔原 缪时英 王琳芳.（2007）. 人睾丸组织特异表达新基因HSD-9的克隆及其编码蛋白质功能，中国医学科学院学报 29（3）：318-323

66. Xiao-Bo Qiu, Song-Ying Ouyang, Chaojun Li, ShiyingMiao, Linfang Wang, and Alfred L. Goldberg. （2006）. hRpn13/ADRM1/GP110 is anovel proteasome subunit that binds the deubiquitinating enzyme,      UCH37.EMBO J. 25：5742-5753

67.X.-B. Qiu,Y.-M.Shao, S.Miao, and L.Wang. （2006）, The diversity of the DnaJ/Hsp40family, the crucial partners for Hsp70 chaperones. Cellular and Molecular LifeSciences 63：2560-2570

68.Ning Liu, Yuan Qiao, Wen Lin Jianchao Zhang, Shiying Miao, Shudong Zong,S.S.Koide and Linfang Wang. （2006）. A sperm component, HSD-3.8 (SPAG1), interacts with G-protein beta1subunit and activates extracellular signal-regulated kinases (ERK). Frontier inBioscience 11:1679-1689

69. Dazhong Zhuang, Yuan Qiao, Xiaodong Zhang, Shiying Miao,Linfang Wang and SS Koide. （2006）. YWK-II Protein/APLP2 in Mouse Gametes: Potential Role inFertilization. Mol. Reprod. Develop 73(1):61-67

70. Dazhong Zhuang, Yong Wang, ChunboYang, Yuan Qiao, Shiying Miao, Samuel S. Koide and Linfang Wang. （2006）. Delineation of the functional domains of the extracellular regionof YWK-II protein/APLP2 of sperm membrane. Frontier in Bioscience 11:2371-2380

71. Chunbo Yang, Shiying Miao, ShudongZong, Samuel S. Koide, Linfang Wang.（2005）Identificationand characterization of rDJL, a novel member of the DnaJ protein family, in rattestis. FEBS letter 579: 5734–5740

72. Samuel S. Koide, Linfang Wang andShiying Miao.（2005）. YWK-II gene: expression ingerm and cancer cells. Trends in Reproductive Biology 1:69-74

73. Xiaoling Tang, Jianchao Zhang, Ying Cai, Shiying Miao, Shudong Zong, S.S. Koide, Linfang Wang. （2004）. Sperm membrane protein (hSMP-1) and RanBPM complex in microtubule-organizingcenter. Journal of Molecular Medicine 82：383－388

74. Yuan QIAO, Ju Xiang YANG, Xiao DongZHANG, Yu LIU, Jian Chao ZHANG, Shu Dong ZONG, Shi Ying MIAO, Lin Fang WANG,Samuel S. KOIDE. （2004）.Characterization of rtSH3p13 gene encoding a development protein involved invesicular traffic in spermiogenesis. Cell Reserch 14(3):197-207

75. Gang Liang, Xiaodong Zhang,Lujing Wang, Yushen Sha, Jianchao Zhang, Shiying Miao, Shudong Zong, LinfangWang,*, and S.S. Koide. （2004）.Identification of Differentially Expressed Genes of Primary SpermatocyteAgainst Round Spermatid Isolated from Human Testis Using the Laser CaptureMicrodissection Technique. Cell Research 14(6):507－512

76. Xiaodong Zhang, Huixian Liu, Yan Zhang,Yuan Qiao, Shiying Miao, Linfang Wang, Jianchao Zhang, Shudong Zong, S. S.Koide. (2003). A novel gene, RSD-3/HSD-3.1, encodes a meiotic-related proteinexpressed in rat and human testis. Journal of Molecular Medicine. 81：380-387

77. Maojun Yang, Binbin Liu, Xiaodong Zhang,Weihong Zhou, Feng Gao, Hai Pang, Shiying Miao , Linfang Wang and Zihe Rao.(2003). Crystallization and preliminary crystallographic analysis of a partialextracellular fragment of a sperm membrane protein YWK-II/APPH related to theAlzheimer bA4-amyloid precursor protein. Acta Crystallographica D59，146-149

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