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1996年升入北京大学生命科学学院临床医学预科专业,2004年毕业于中国协和医科大学(现“北京协和医学院”),获得临床医学博士学位。2009年完成北京协和医院内科轮转及内科总值班轮岗,被聘为北京协和医院风湿免疫科主治医师,2015年聘为北京协和医院风湿免疫科副主任医师。先后担任内科教学秘书及风湿免疫科教学秘书职务,并于北京协和医院教育处博后办公室兼职。先后承担并参与国家自然科学基金项目3项、国家科技部重点项目3项,以第一作者及通讯作者发表SCI论文及综述二十余篇,国内核心期刊文章三十余篇。担任中文核心期刊《中华临床免疫与变态反应杂志》编委,并为多家SCI期刊和国内核心期刊审稿。已培养科研型硕士研究生3人,带教协和医学院学生60余人。
带教学生均在国内外会议投稿多次,获得壁报交流机会。学生除完成学位论文要求外,均发表多篇中文核心及SCI文章。依托平台技术成熟,团队氛围融洽,设备齐全。
系统性血管炎及类风湿关节炎发病机制及转化医学研究,与清华大学药学院建立长期合作关系。
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支持扩展名:.rar .zip .doc .docx .pdf .jpg .png .jpeg目前主要从事:
1,系统性血管炎发病机制研究及临床研究
2,类风湿关节炎发病机制研究、临床研究及转化医学研究
3,系统性红斑狼疮临床研究及转化医学研究
近年发表部分文章:
1,代表性论著(10篇)
① Li J#, Wang X#, Zhang F, Yin H*. Toll-like receptors as therapeutic targets for autoimmune connective tissue diseases. Pharmacol Ther. 2013. 138(3): 441-51. (First author, IF 10.3)(医学1区)
② Li J#, Csakai A, Jin J, Zhang F, Yin H*. Therapeutic Developments Targeting Toll-like Receptor-4-Mediated Neuroinflammation. ChemMedChem. 2016;11(2):154-165. (First author, IF 3.083) (医学3区)
③ Shuting Zhang, Zhenyi Hu, Hiromi Tanji, Shuangshuang Jiang, Nabanita Das, Jing Li, Kentaro Sakaniwa, Jin Jin, Yanyan Bian, Umeharu Ohto, Toshiyuki Shimizu, Hang Yin. Small-molecule inhibition of TLR8 through stabilization of its resting state. Nat Chem Biol. 2018;14(1):58-64. (IF 13.688)(生物1区)
④ Jing Li#, Yunjiao Yang, Jiuliang Zhao, Mengtao Li, Xinping Tian, Xiaofeng Zeng*. The efficacy of Mycophenolate mofetil for the treatment of Chinese Takayasu’s arteritis. Scientific Reports . 2016;6:38687. (First author, IF 4.131)(综合性期刊3区)
⑤ Jing L#, Fei Sun Zhe Chen, Yunjiao Yang, Jiuliang Zhao, Mengtao Li, Xinping Tian, Xiaofeng Zeng*. The clinical characteristics of Chinese Takayasu’s arteritis patients: a retrospective study of 411 patients over 24 years. Arthritis Res Ther. 2017 May 25;19(1):107. (First author, IF 5.156)(医学2区)
⑥ Li J, Wang Y, Wang Y, et al. Association between acute phase reactants, interleukin-6, tumor necrosis factor-α, and disease activity in Takayasu's arteritis patients [J]. Arthritis research & therapy, 2020, 22(1): 285. (First author, IF 5.156)(医学2区)
⑦ Tian Y, Li J, Tian X, et al. Using the co-expression network of T cell-activation-related genes to assess the disease activity in Takayasu's arteritis patients [J]. Arthritis research & therapy, 2021, 23(1): 303. (Corresponding author, IF 5.156)(医学2区)
⑧ Tian Y, Huang B, Li J, et al. Identification of the Association Between Toll-Like Receptors and T-Cell Activation in Takayasu’s Arteritis [J]. Frontiers in immunology, 2022, 12(1) (Corresponding author, IF 7.561)(免疫学2区)
⑨ J Li, M Li, D Wu, J Zhou, S Leung, F Zhang. SM03, an anti-human CD22 monoclonal antibody, for active rheumatoid arthritis: a phase II randomized, double-blind, placebo-controlled study. Rheumatology(Oxford). 2021, keab699 (First author, IF 7.58)(医学2区)
⑩ Li J, Li M, Tian X, Zeng X. Tofacitinib in Patients With Refractory Takayasu's Arteritis. Rheumatology(Oxford).2020,keaa281. (First author, IF 7.58)(医学2区)
2,其他研究成果
① 田苡箫,杨云娇,李菁*.大动脉炎患者外周血单个核细胞中Toll样受体和程序性死亡受体1的表达[J].中华临床免疫和变态反应杂志,2020,14(2):92-98.
② 田苡箫,李菁*.大动脉炎患者外周血单个核细胞RT-qPCR内参基因的选择[J].基础医学与临床, 2021,41(1):87-92.
③ 李菁#,朱孟铸,杨云娇,张文,田新平*. 多发性大动脉炎合并活动性结核感染36例的病例对照研究[J].中华风湿病学杂志,2016,20(3):176-180
④ Jing Li#, Hongchao Li, Fei Sun, Zhe Chen, Yunjiao Yang, Jiuliang Zhao, Mengtao Li, Xinping Tian, Xiaofeng Zeng*4. Clinical characteristics of heart involvement in Chinese Takayasu’s arteritis patients. J Rheumatol. 2017 Aug 15. pii: jrheum.161514. (First author, IF 3.418)(医学3区)
⑤ Xu Q#, Zhu G, Li J*, Cheng K. Development of Antibacterial Drugs by Targeting Toll-Like Receptors. Current Topics in Medicinal Chemistry, 2017, 17, 270-277. (Corresponding author, IF 3.227) (医学3区)
⑥ Li J#, Wang Q#, Zheng W*, Ma J, Zhang W, Wang W, Tian X. Hemophagocytic lymphohistiocytosis: clinical analysis of 103 adult patients. Medicine (Baltimore). 2014. 93(2): 100-5. (First author, IF 1.87) (医学4区)
⑦ Li J#, Leng X, Li Z, Ye Z, Li C, Li X, Zhu P, Wang Z, Zheng Y, Li X, Zhang M, Tian XP, Li M, Zhao J, Zhang FC, Zhao Y, Zeng X*. Chinese SLE treatment and research group registry: III. association of autoantibodies with clinical manifestations in Chinese patients with systemic lupus erythematosus. J Immunol Res. 2014. 2014: 809389. (First author, IF 3.326) (医学3区)
⑧ Li J#, Wu H, Huang X, Xu D, Zheng W*, Zhao Y, Liu W, Zeng X. Clinical analysis of 56 patients with rhupus syndrome: manifestations and comparisons with systemic lupus erythematosus: a retrospective case-control study. Medicine (Baltimore). 2014. 93(10): e49. (First author, IF 1.87)(医学4区)
⑨ Jing Li#, Mengzhu Zhu, Mengtao Li, Wenjie Zheng, Jiuliang Zhao, Xinping Tian, Xiaofeng Zeng*. Cause of death in Chinese Takayasu arteritis patients. Medicine (2016) 95:27(e4069). (First author, IF 1.87)(医学4区)
⑩ Yixiao, Tian; Jing Li*; Xinping Tian; Xiaofeng Zeng. Activation of Toll-like Receptors in Peripheral Blood Mononuclear Cells of Takayasu’s Arteritis Patients. European Congress of Rheumatology, Frankfurt, German, 2020. FRI0017.(国际A类会议论文)
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