1、国家自然科学基金，DNAJB6在结直肠癌侵袭转移中的作用及分子机制，主持

2、中国医学科学院肿瘤医院多学科联合重点课题，术前化疗联合侧方淋巴结清扫在侧方淋巴结肿大直肠癌中应用的Ⅱ期临床研究，主持

3、首都卫生发展科研专项项目，腹腔镜直乙状结肠癌切除经肛门标本取出术标准化的研究，子课题负责人

4、湖北陈孝平科技发展基金，基于真实世界槐耳颗粒辅助治疗结直肠癌的临床研究，主持

5、北京协和医学院协和青年基金，纳米碳导航指导直肠癌精准微创手术的前瞻性研究，主持

6、院所基本科研业务费预探索项目，预测直肠癌淋巴结转移和预后的蛋白标志物研，主持

7、院所基本科研业务费青年项目，Ⅱ期结直肠癌术后转移和预后的标志物研究，主持

8、国家重点研发计划，结直肠癌精准靶向治疗新靶点的高通量功能性筛选以及分子作用机理研究，参加

1、国家自然科学基金，DNAJB6在结直肠癌侵袭转移中的作用及分子机制，主持

2、中国医学科学院肿瘤医院联合攻关课题，术前FOLFOXIRI化疗联合侧方淋巴结清扫在中低位直肠癌伴侧方淋巴结转移中应用的前瞻性、多中心随机对照研究，主持

3、中国中医科学院科技创新工程重点协同攻关羡慕，中医肿瘤药食同源膳品在恶性肿瘤防治过程中的干预作用的示范研究，子课题负责人

2、中国医学科学院肿瘤医院多学科联合重点课题，术前化疗联合侧方淋巴结清扫在侧方淋巴结肿大直肠癌中应用的Ⅱ期临床研究，主持

3、首都卫生发展科研专项项目，腹腔镜直乙状结肠癌切除经肛门标本取出术标准化的研究，子课题负责人

4、湖北陈孝平科技发展基金，基于真实世界槐耳颗粒辅助治疗结直肠癌的临床研究，主持

5、北京协和医学院协和青年基金，纳米碳导航指导直肠癌精准微创手术的前瞻性研究，主持

6、院所基本科研业务费预探索项目，预测直肠癌淋巴结转移和预后的蛋白标志物研，主持

7、院所基本科研业务费青年项目，Ⅱ期结直肠癌术后转移和预后的标志物研究，主持

8、国家重点研发计划，结直肠癌精准靶向治疗新靶点的高通量功能性筛选以及分子作用机理研究，参加

科研奖励

1、直肠癌综合治疗关键技术的建立、优化及推广，北京市，北京市科学技术奖，二等奖

2、结直肠癌治疗关键技术的优化与推广应用，中国医疗保健国际交流促进会，华夏医学科技奖，一等奖

3、结直肠癌治疗关键技术的优化与推广应用，中华医学会，中华医学科技奖，三等奖

专利

1. DNAJB6、Hsp70及Hsp90α的组合在II期结直肠癌预后判断中的应用，2017.11.07，中国，ZL201711083883.7

1.Zhang TT, Zhu YQ, Cai HQ, Zheng JW, Hao JJ, Chang C, Cai Y, Wang MR, Liang JW*, Zhang Y*. The Prognostic Role of Aberrant mTOR Activation in Patients with Stage II and III Colorectal Cancer. Biomarkers in Medicine, 2020, Accepted.

2. Zhou Si Cheng, Wang Xue Wei, Zhao Chuan Duo, Zhou Hai Tao, Pei Wei, Liang Jian Wei*, Zhou Zhi Xiang, Wang Xi Shan, Can transanal natural orifice specimen extraction after laparoscopic anterior resection for colorectal cancer reduce the inflammatory response? Journal of gastroenterology and hepatology, 2020, 35(6): 1016-1022. 

3. Sicheng Zhou, Wei Pei, Zijin Li, Haitao Zhou, Jianwei Liang, Qian Liu, Zhixiang Zhou, Xishan Wang. Evaluating the predictive factors for anastomotic leakage after total laparoscopic resection with transrectal natural orifice specimen extraction for colorectal cancer. Pac J Clin Oncol. 2020 Jun 7. 

4. Zhou Si Cheng#, Tian Yan Tao#, Wang Xue Wei, Zhao Chuan Duo, Ma Shuai, Jiang Jun, Li Er Ni, Zhou Hai Tao, Liu Qian, Liang Jian Wei*, Zhou Zhi Xiang, Wang Xi Shan, Application of indocyanine green-enhanced near-infrared fluorescence-guided imaging in laparoscopic lateral pelvic lymph node dissection for middle-low rectal cancer, World Journal of Gastroenterology, 2019, 25(31): 4502-4511.

5. Wang Peng#, Liang Jian Wei#, Zhou Hai Tao, Wang Zheng, Zhou Zhi Xiang*, Surgical specimen extraction via a prophylactic ileostomy procedure: A minimally invasive technique for laparoscopic rectal cancer surgery, World Journal of Gastroenterology, 2018, 24(1): 104-111.

6. Liang Jian Wei, Shi Zhi Zhou*, Shen Tian Yun, Che Xu, Wang Zheng, Shi Su Sheng, Xu Xin, Cai Yan, Zhao Ping, Wang Cheng Feng, Zhou Zhi Xiang, Wang Ming Rong*, Identification of genomic alterations in pancreatic cancer using array-based comparative genomic hybridization, PLoS ONE, 9(12): e114616. 

7. Liang Jian Wei#, Shi Zhi Zhou#, Zhang Tong Tong, Hao Jia Jie, Wang Zheng, Wang Xiao Min, Yang Hai, Wang Ming Rong, Zhou Zhi Xiang*, Zhang Yu*, Analysis of genomic aberrations associated with the clinicopathological parameters of rectal cancer by array-based comparative genomic hybridization, Oncology Reports, 29(5): 1827-34.

8. PengWang, HaitaoZhou, ZhixiangZhou, JianweiLiang.  Mesenteric Fibromatosis Misdiagnosed With Lymph Node Metastasis After Successful Laparoscopic Right Hemicolectomy: A Report of Two Cases With Review of Literature. Onco Targets Ther. 2018 Aug 13;11:4811-4816.

9. Sicheng Zhou # , Xuewei Wang # , Chuanduo Zhao, Wei Pei, Haitao Zhou, Qian Liu, Jianwei Liang, Zhixiang Zhou, Xishan Wang. Comparison of short-term and survival outcomes for transanal natural orifice specimen extraction with conventional mini-laparotomy after laparoscopic anterior resection for colorectal cancer. Cancer Manag Res. 2019 Jul 1;11:5939-5948.

10. P Wang, S Zhou, H Zhou, J Liang, Z Zhou. Evaluating predictive factors for determining the presence of lateral pelvic node metastasis in rectal cancer patients following neoadjuvant chemoradiotherapy. Colorectal Dis. 2019 Jul;21(7):791-796.

11. Sicheng Zhou, Haitao Zhou, Zhaoxu Zheng, Jianwei Liang, Zhixiang Zhou, Xishan Wang. Predictive risk factors for anastomotic leakage after anterior resection of rectal cancer in elderly patients over 80 years old:an analysis of 288 consecutive patients. World J Surg Oncol. 2019 Jun 29;17(1):112. 

12. Sicheng Zhou, Xuewei Wang, Chuanduo Zhao, Qian Liu, Haitao Zhou, Zhaoxu Zheng, Zhixiang Zhou, Xishan Wang, Jianwei Liang. Laparoscopic vs open colorectal cancersurgery in elderly patients: short- and long-term outcomes and predictors for overall and disease-free survival. BMC Surg. 2019 Sep 14;19(1):137.

13. Zhou SC, Pei W, Sun Z, Zhou ZX, Wang XS, Liang JW, Feng Q. Clinicopathological characteristics and prognostic factors for the recurrence of abdominal desmoid tumors: a retrospective study of 113 patients from two Chinese hospitals. Chin Med J (Engl). 2020 Dec 21;134(12):1505-1507.

14. Zhou S, Jiang Y, Liang J, Pei W, Zhou Z. Neoadjuvant chemotherapy followed by hyperthermic intraperitoneal chemotherapy for patients with colorectal peritoneal metastasis: a retrospective study of its safety and efficacy.World J Surg Oncol. 2021 May 17;19(1):151.

 15. Zhou S, Jiang Y, Pei W, Zhou H, Liang J, Zhou Z.Neoadjuvant chemoradiotherapy followed by lateral pelvic lymph node dissection for rectal cancer patients: A retrospective study of its safety and indications. J Surg Oncol. 2021 Apr 21.

16. Zhou S, Feng Q, Zhang J, Zhou H, Jiang Z, Liang J, Pei W, Liu Q, Zhou Z, Wang X. Can Elderly Patients with Peritoneal Metastasis Induced by Appendiceal or Colorectal Tumours Benefit from Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC)? Clin Interv Aging. 2021 Mar 30;16:559-568.

17. Zhou S, Feng Q, Zhang J, Zhou H, Jiang Z, Liu Z, Zheng Z, Chen H, Wang Z, Liang J, Pei W, Liu Q, Zhou Z, Wang X. High-grade postoperative complications affect survival outcomes of patients with colorectal Cancer peritoneal metastases treated with Cytoreductive surgery and Hyperthermic Intraperitoneal chemotherapy.BMC Cancer. 2021 Jan 7;21(1):41.

 18. Pei W, Zhou S, Zhang J, Zhou H, Chen H, Bi J, Zheng Z, Liu Z, Jiang Z, Wang Z, Liu Q, Wang X, Liang J, Feng Q. Lobaplatin-Based Hyperthermic Intraperitoneal Chemotherapy for Patients with Peritoneal Metastasis from Appendiceal and Colorectal Cancer: Safety and Efficacy Profiles. Cancer Manag Res. 2020 Nov 24;12:12099-12110.

19. Zhou S, Pei W, Li Z, Zhou H, Liang J, Liu Q, Zhou Z, Wang X. Evaluating the predictive factors for anastomotic leakage after total laparoscopic resection with transrectal natural orifice specimen extraction for colorectal cancer. Asia Pac J Clin Oncol. 2020 Dec;16(6):326-332.

 20. Zhou S, Wang X, Zhao C, Zhou H, Pei W, Liang J, Zhou Z, Wang X.J. Can transanal natural orifice specimen extraction after laparoscopic anterior resection for colorectal cancer reduce the inflammatory response? Gastroenterol Hepatol. 2020 Jun;35(6):1016-1022.